Ordering RecommendationRecommendations when to order or not order the test. May include related or preferred tests.
Assesses for single gene mutations, including substitutions and smaller insertions and deletions that may have implications for prognosis or clinical management in patients with chronic lymphocytic leukemia or other B-cell lymphoproliferative disorders.
MnemonicUnique test identifier.
CLL NGS
MethodologyProcess(es) used to perform the test.
Massively Parallel Sequencing
PerformedDays of the week the test is performed.
Varies
ReportedExpected turnaround time for a result, beginning when ARUP has received the specimen.
12-14 days
New York DOH Approval StatusIndicates test has been approved by the New York State Department of Health.
Specimens from New York clients will be sent out to a New York DOH approved laboratory, if possible.
Specimen Required
Patient Preparation
Collect
Lavender (EDTA), Green (sodium heparin), Bone Marrow (EDTA), or Bone Marrow (sodium heparin). Fresh-frozen tissue
Specimen Preparation
Whole Blood and Bone Marrow: Transport 3 mL. (Min: 1.5 mL) Fresh-frozen Tissue: Transport 5 mg fresh-frozen tissue. (Min: 5 mg) Separate specimens must be submitted when multiple tests are ordered
Storage/Transport Temperature
Whole Blood or Bone Marrow: Refrigerated. Fresh-frozen Tissue: Frozen.
Reference IntervalNormal range/expected value(s) for a specific disease state. May also include abnormal ranges.
By report
Interpretive DataBackground information for test. May include disease information, patient result explanation, recommendations, details of testing, associated diseases, explanation of possible patient results.
CPT CodesThe American Medical Association Current Procedural Terminology (CPT) codes published in ARUP's Laboratory Test Directory are provided for informational purposes only. The codes reflect our interpretation of CPT coding requirements based upon AMA guidelines published annually. CPT codes are provided only as guidance to assist clients with billing. ARUP strongly recommends that clients confirm CPT codes with their Medicare administrative contractor, as requirements may differ. CPT coding is the sole responsibility of the billing party. ARUP Laboratories assumes no responsibility for billing errors due to reliance on the CPT codes published.
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
AliasesOther names that describe the test. Synonyms.
Lymphocytosis
NHL
Chronic lymphocytic leukemia
CLL
CLL/SLL
Mantle cell lymphoma
MBL
MCL
Monoclonal B-cell lymphocytosis
Non-Hodgkin lymphoma
SLL
Small lymphocytic leukemia
Chronic Lymphocytic Leukemia Mutation Panel by Next Generation Sequencing