Assesses for single gene mutations, including substitutions and smaller insertions and deletions that may have implications for prognosis or clinical management in patients with chronic lymphocytic leukemia or other B-cell lymphoproliferative disorders.
Massively Parallel Sequencing
Lavender (EDTA), Green (sodium heparin), Bone Marrow (EDTA), or Bone Marrow (sodium heparin). Fresh-frozen tissue
Whole Blood and Bone Marrow: Transport 3 mL. (Min: 1.5 mL)
Fresh-frozen Tissue: Transport 5 mg fresh-frozen tissue. (Min: 5 mg)
Separate specimens must be submitted when multiple tests are ordered
Whole Blood or Bone Marrow: Refrigerated.
Fresh-frozen Tissue: Frozen.
Serum, plasma, grossly hemolyzed specimens, buccal brush or swab, FFPE tissue.
Whole Blood or Bone Marrow: Ambient: 72 hours; Refrigerated: 1 week; Frozen: Unacceptable
Fresh-frozen Tissue: Ambient: Unacceptable; Refrigerated: Unacceptable; Frozen: 1 month
Refer to report.
Laboratory Developed Test (LDT)
Genes tested: ATM, BCL2, BIRC3*, BRAF, BTG1, BTK, CARD11, CD79B, CXCR4, DDX3X, FBXW7, IKZF3, KRAS, MAP2K1, MED12, MGA, MYD88, NOTCH1, NRAS, PLCG2, POT1, RPS15*, SAMHD1, SF3B1, TP53, XPO1, ZMYM3
* - One or more exons are not covered by sequencing for the indicated gene; see Additional Technical Information test fact sheet.
|Component Test Code*||Component Chart Name||LOINC|
|3001859||Chronic Lymphocytic Leukemia Specimen||31208-2|
|3001860||Chronic Lymphocytic Leukemia Interp||35506-5|
|3002513||EER, CLL Panel by NGS||11526-1|
- Chronic lymphocytic leukemia
- Mantle cell lymphoma
- Monoclonal B-cell lymphocytosis
- Non-Hodgkin lymphoma
- Small lymphocytic leukemia