Use to assess for single gene variants, including substitutions and smaller insertions and deletions that may have implications for prognosis or clinical management in patients with chronic lymphocytic leukemia (CLL) or other B-cell lymphoproliferative disorders.
Massively Parallel Sequencing
New York DOH Approval Status
Lavender (EDTA), Green (sodium heparin), Bone Marrow (EDTA), or Bone Marrow (sodium heparin). Fresh-frozen tissue.
New York State Clients: Lavender (EDTA)
Whole Blood and Bone Marrow: Transport 3 mL. (Min: 1.5 mL)
Fresh-frozen Tissue: Transport 5 mg fresh-frozen tissue. (Min: 5 mg)
Separate specimens must be submitted when multiple tests are ordered.
New York State Clients: Transport 5 mL whole blood (Min: 2 mL) or 2 mL bone marrow (Min: 2 mL).
Whole Blood or Bone Marrow: Refrigerated.
Fresh-frozen Tissue: Frozen.
Serum, plasma, grossly hemolyzed specimens, buccal brush or swab, FFPE tissue.
Whole Blood or Bone Marrow: Ambient: 72 hours; Refrigerated: 1 week; Frozen: Unacceptable
Fresh-frozen Tissue: Ambient: Unacceptable; Refrigerated: Unacceptable; Frozen: 1 month
New York State Clients: Ambient: 72 hours; Refrigerated: 4 days; Frozen: Unacceptable
Refer to report.
This test was developed and its performance characteristics determined by ARUP Laboratories. It has not been cleared or approved by the U.S. Food and Drug Administration. This test was performed in a CLIA-certified laboratory and is intended for clinical purposes.
Laboratory Developed Test (LDT)
Genes tested: ATM; BCL2; BIRC3*; BRAF; BTG1; BTK; CARD11; CD79B; CXCR4; DDX3X; FBXW7; IKZF3; KRAS; MAP2K1; MED12; MGA; MYD88; NOTCH1; NRAS; PLCG2; POT1; RNASEH2A; RNASEH2B; RPS15*; SAMHD1; SF3B1; TP53; XPO1; ZMYM3
*One or more exons are not covered by sequencing for the indicated gene; see Additional Technical Information test fact sheet.
|Component Test Code*||Component Chart Name||LOINC|
|3001859||Chronic Lymphocytic Leukemia Specimen||31208-2|
|3001860||Chronic Lymphocytic Leukemia Interp||35506-5|
|3002513||EER, CLL Panel by NGS||11526-1|
- Chronic lymphocytic leukemia
- Mantle cell lymphoma
- Monoclonal B-cell lymphocytosis
- Non-Hodgkin lymphoma
- Small lymphocytic leukemia