BRCA1 and BRCA2-Associated HBOC Syndrome Panel, Sequencing and Deletion/Duplication
Recommended test to confirm BRCA1- and BRCA2-associated hereditary breast and ovarian cancer (HBOC) syndrome. Testing minors for adult-onset conditions is not recommended; testing will not be performed in minors without prior approval. For additional information, please contact an ARUP genetic counselor at 800-242-2787 ext. 2141.
To compare this test to other hereditary cancer panels, refer to the Hereditary Cancer Panel Comparison table.
Massively Parallel Sequencing
New York DOH Approval Status
Lavender or pink (EDTA) or yellow (ACD solution A or B).
Transport 3 mL whole blood. (Min: 2 mL)
Serum or plasma; grossly hemolyzed or frozen specimens; saliva, buccal brush, or swab; FFPE tissue.
Ambient: 72 hours; Refrigerated: 1 week; Frozen: Unacceptable
Refer to report.
Laboratory Developed Test (LDT)
Genes tested: BRCA1* (NM_007294), BRCA2 (NM_000059)
*One or more exons are not covered by deletion/duplication analysis for the indicated gene; see Additional Technical Information.
|Component Test Code*||Component Chart Name||LOINC|
- Hereditary Breast
- Ovarian Cancer