BRCA1 and BRCA2-Associated HBOC Syndrome Panel, Sequencing and Deletion/Duplication
Germline analysis of the BRCA1 and BRCA2 genes in individuals with a suspected diagnosis of hereditary breast and ovarian cancer (HBOC) syndrome. When a relative has a previously identified pathogenic sequence variant, see Familial Mutation, Targeted Sequencing (2001961).
Massively Parallel Sequencing/Multiplex Ligation-dependent Probe Amplification
Lavender (EDTA) or Yellow (ACD Solution A or B).
Transport 3 mL whole blood. (Min: 2 mL)
Serum or plasma; grossly hemolyzed or frozen specimens
Ambient: 72 hours; Refrigerated: 1 week; Frozen: Unacceptable
Refer to report.
Laboratory Developed Test (LDT)
Genes tested: BRCA1 (NM_007294), BRCA2 (NM_000059)
|Component Test Code*||Component Chart Name||LOINC|
- Hereditary Breast
- Ovarian Cancer