Toxigenic Clostridioides difficile by LFA with Reflex to PCR, Stool
Glutamate dehydrogenase (GDH) antigen and toxin A/B testing for suspected Clostridioides (Clostridium) difficile infection, with reflex to polymerase chain reaction (PCR).
New York DOH Approval Status
Liquid or soft stool.
Transfer 1.0 mL stool to a clean, unpreserved transport vial (ARUP Supply# 40910). Available online through eSupply using ARUP Connect (TM) or contact ARUP Client Services at 800-522-2787. (Min: 0.5 mL).
Refrigerated. Also acceptable: Frozen.
Specimens preserved in Cary Blair/C&S media, formalin-based fixative (eg, Formalin, SAF) or alcohol-based fixative (eg, PVA, Totalfix, Alcorfix, etc). Formed stool.
Ambient 2 hours; Refrigerated 72 hours; Frozen 1 week
Qualitative Lateral Flow Immunoassay/Qualitative Polymerase Chain Reaction (PCR)
Within 24 hours
Refer to report
If C. difficile GDH antigen is detected by LFA but C. difficile toxin is not detected, C. difficile tcdB gene by PCR will be performed; additional charges apply.
87324; 87899; if reflexed, add 87493
|Component Test Code*||Component Chart Name||LOINC|
|3001805||Toxigenic C. difficile Interpretation||34712-0|
- C diff
- C diff antigen
- C diff toxin
- Clostridioides difficle
- Clostridium difficile