May be useful for differential evaluation of polymyositis, dermatomyositis, necrotizing autoimmune myopathy, or overlap syndromes associated with connective tissue disease.
Qualitative Immunoprecipitation/Semi-Quantitative Multiplex Bead Assay/Qualitative Immunoblot
Sun-Sat
7-18 days
Serum Separator Tube (SST).
Separate from cells ASAP or within 2 hours of collection. Transfer three 1 mL serum aliquots to ARUP Standard Transport Tubes. (Min: 0.5 mL/aliquot)
Refrigerated.
Hemolyzed, hyperlipemic, icteric, heat-treated or contaminated specimens.
Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year
Test Number |
Components |
Reference Interval |
|||||||||
---|---|---|---|---|---|---|---|---|---|---|---|
2012074 | SSA 52 and 60 (Ro) (ENA) Antibodies, IgG |
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0050470 | Smith/RNP (ENA) Antibody, IgG |
|
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0099592 | Jo-1 Antibody, IgG |
|
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2012173 | Fibrillarin (U3 RNP) Antibody, IgG | Negative | |||||||||
2003040 | PM/Scl-100 Antibody, IgG by Immunoblot | Negative | |||||||||
Mi-2 (nuclear helicase protein) Antibody | Negative | ||||||||||
PL-7 (threonyl-tRNA synthetase) Antibody | Negative | ||||||||||
PL-12 (alanyl-tRNA synthetase) Antibody | Negative | ||||||||||
P155/140 Antibody | Negative | ||||||||||
EJ (glycyl-tRNA synthetase) Antibody | Negative | ||||||||||
Ku Antibody | Negative | ||||||||||
SRP (Signal Recognition Particle) Ab | Negative | ||||||||||
OJ (isoleucyl-tRNA synthetase) Antibody | Negative | ||||||||||
SAE1 (SUMO activating enzyme) Ab | Negative | ||||||||||
MDA5 (CADM-140) Ab | Negative | ||||||||||
NXP2 (Nuclear matrix protein-2) Ab | Negative | ||||||||||
TIF-1 gamma (155 kDa) Ab | Negative |
Refer to report.
This test was developed and its performance characteristics determined by ARUP Laboratories. It has not been cleared or approved by the US Food and Drug Administration. This test was performed in a CLIA certified laboratory and is intended for clinical purposes.
Laboratory Developed Test (LDT)
Antibodies: Mi-2, PL-7, PL12, P155/140, EJ, Ku, OJ, PM/Scl, SRP, Smith/RNP, Ro52, Ro60, Jo-1, U3 Fib, SAE1, NXP2, MDA5, TIF1-gamma
Hotline History
83516 x8; 86235 x6; 84182 x4
Component Test Code* | Component Chart Name | LOINC |
---|---|---|
0050470 | Smith/RNP (ENA) Ab, IgG | 33983-8 |
0050691 | SSA-52 (Ro52) (ENA) Antibody, IgG | 31625-7 |
0099592 | Jo-1 (Histidyl-tRNA Synthetase) Ab, IgG | 33571-1 |
2003041 | PM/Scl 100 Antibody, IgG | 81732-0 |
2010852 | Mi-2 (nuclear helicase protein) Antibody | 18485-3 |
2010853 | PL-7 (threonyl-tRNA synthetase) Antibody | 33772-5 |
2010854 | PL-12 (alanyl-tRNA synthetase) Antibody | 33771-7 |
2010855 | P155/140 Antibody | |
2010856 | EJ (glycyl-tRNA synthetase) Antibody | 45149-2 |
2010857 | Ku Antibody | 18484-6 |
2010859 | SRP (Signal Recognition Particle) Ab | 33921-8 |
2010860 | OJ (isoleucyl-tRNA synthetase) Antibody | 45152-6 |
2012055 | SSA-60 (Ro60) (ENA) Antibody, IgG | 53019-6 |
2012174 | Fibrillarin (U3 RNP) Ab, IgG | 49963-2 |
2013994 | Myositis Panel Interpretive Data | 48767-8 |
3001786 | SAE1 (SUMO activating enzyme) Ab | 82440-9 |
3001787 | MDA5 (CADM-140) Ab | 82424-3 |
3001788 | NXP2 (Nuclear matrix protein-2) Ab | 82426-8 |
3001789 | TIF-1 gamma (155 kDa) Ab | 82448-2 |