Ordering Recommendation
Use to determine etiology of long QT syndrome (LQTS) in symptomatic individuals. Useful for presymptomatic testing in individuals with a family history of LQTS or sudden cardiac death.
Mnemonic
Methodology
Massively Parallel Sequencing
Performed
Varies
Reported
14-21 days
New York DOH Approval Status
Specimen Required
Lavender or pink (EDTA) or yellow (ACD solution A or B).
Transport 3 mL whole blood. (Min: 2 mL)
Refrigerated.
Serum or plasma; grossly hemolyzed or frozen specimens; saliva, buccal brush, or swab; FFPE tissue.
Ambient: 72 hours; Refrigerated: 1 week; Frozen: Unacceptable
Reference Interval
By report
Interpretive Data
Refer to report.
This test was developed and its performance characteristics determined by ARUP Laboratories. It has not been cleared or approved by the US Food and Drug Administration. This test was performed in a CLIA certified laboratory and is intended for clinical purposes.
Counseling and informed consent are recommended for genetic testing. Consent forms are available online.
Laboratory Developed Test (LDT)
Note
CACNA1C; CALM1*; CALM2; CALM3; KCNE1*; KCNE2*; KCNH2*; KCNJ2; KCNQ1; SCN5A; TRDN
*One or more exons are not covered by sequencing and/or deletion/duplication analysis for the indicated gene; see additional technical information.
Hotline History
Hotline History
CPT Codes
81403; 81404; 81406; 81407; 81414; 81479
Components
Component Test Code* | Component Chart Name | LOINC |
---|---|---|
3001604 | Long QT Interp | 41103-3 |
3001681 | Long QT Specimen | 31208-2 |
Aliases
- Andersen-Tawil syndrome
- Jervell and Lange-Nielson syndrome
- JLNS
- LQTS
- Timothy syndrome
- torsades de pointes