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Hypersensitivity Pneumonitis Extended Panel (Farmer's Lung Panel)
Ordering Recommendation
Use to evaluate patients suspected of having hypersensitivity pneumonitis induced by exposure to Aspergillus flavus, Aspergillus fumigatus, Aurebasidium pullulans, Micropolyspora faeni, Saccharomonospora viridis, Thermoactinomyces candidus, or pigeon serum.
New York DOH Approval Status
Specimen Required
Serum separator tube (SST).
Separate from cells ASAP or within 2 hours of collection. Transfer two 2.5 mL aliquots of serum to individual ARUP standard transport tubes. (Min: 1.6 mL total, 0.8 mL in two aliquots)
Refrigerated.
Plasma. Contaminated, hemolyzed, or severely lipemic specimens.
After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles)
Methodology
Qualitative Immunodiffusion/Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay
Performed
Sun-Sat
Reported
3-7 days
Reference Interval
| Test Number |
Components |
Reference Interval |
||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Allergen, Fungi/Mold, Phoma betae IgE |
|
|||||||||||||
| T. candidus Ab, Precipitin | None detected | |||||||||||||
| S. viridis Ab, Precipitin | None detected | |||||||||||||
| A. fumigatus #3 Ab, Precipitin | None detected | |||||||||||||
| A. fumigatus #2 Ab, Precipitin | None detected | |||||||||||||
| A. flavus Ab, Precipitin | None detected | |||||||||||||
| M. faeni Ab, Precipitin | None detected | |||||||||||||
| Pigeon Serum Ab, Precipitin | None detected | |||||||||||||
| A. pullulans Ab, Precipitin | None detected | |||||||||||||
| A. fumigatus #6 Ab, Precipitin | None detected | |||||||||||||
| A. fumigatus #1 Ab, Precipitin | None detected | |||||||||||||
| Allergen, Animal, Feather Mix IgE | Negative |
Interpretive Data
Allergen results of 0.10-0.34 kU/L are intended for specialist use as the clinical relevance is undetermined. Even though increasing ranges are reflective of increasing concentrations of allergen-specific IgE, these concentrations may not correlate with the degree of clinical response or skin testing results when challenged with a specific allergen. The correlation of allergy laboratory results with clinical history and in vivo reactivity to specific allergens is essential. A negative test may not rule out clinical allergy or even anaphylaxis.
FDA
Note
Testing includes antibodies directed at Aspergillus fumigatus #1, A. fumigatus #2, A. fumigatus #3, A. fumigatus #6, A. flavus, Aureobasidium pullulans, Micropolyspora faeni, T. candidus, Saccharomonospora viridis, and pigeon serum. Testing also includes the following allergens: feather mix and Phoma betae.
Hotline History
Hotline History
CPT Codes
86003; 86005; 86331 x5; 86606 x5
Components
| Component Test Code* | Component Chart Name | LOINC |
|---|---|---|
| 0055037 | Allergen, Animal, Feather Mix IgE | 31161-3 |
| 0055041 | Allergen, Interp, Immunocap Score IgE | 48767-8 |
| 0055066 | A. fumigatus #1 Ab, Precipitin | 6808-0 |
| 0055067 | A. fumigatus #6 Ab, Precipitin | 6809-8 |
| 0055068 | A. pullulans Ab, Precipitin | 6810-6 |
| 0055069 | Pigeon Serum Ab, Precipitin | 6733-0 |
| 0055071 | M. faeni Ab, Precipitin | 6818-9 |
| 0055220 | A. flavus Ab, Precipitin | 23820-4 |
| 0055221 | A. fumigatus #2 Ab, Precipitin | 30036-8 |
| 0055222 | A. fumigatus #3 Ab, Precipitin | 15151-4 |
| 0055223 | S. viridis Ab, Precipitin | 15209-0 |
| 0055224 | T. candidus Ab, Precipitin | 21560-8 |
| 0055390 | Allergen, Fungi/Mold, Phoma betae IgE | 6216-6 |
Aliases
- farmer's lung panel
- Hyper Pneumo
- HP
- hypersensitivity pneumonitis
