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3001508
CYP2C19
2C19GENO
Ordering Recommendation
Assesses genetic risk of abnormal drug metabolism for CYP2C19 substrates. May aid in drug selection and dose planning for drugs metabolized by CYP2C19.
New York DOH Approval Status
This test is New York state approved.
Specimen Required
Patient Preparation
Collect
Lavender (EDTA), pink (K2EDTA), or yellow (ACD solution A or B).
Specimen Preparation
Transport 3 mL whole blood. (Min: 1 mL)
Storage/Transport Temperature
Refrigerated.
Unacceptable Conditions
Plasma or serum. Specimens collected in sodium heparin or lithium heparin. Frozen specimens in glass collection tubes.
Remarks
Stability
Ambient: 72 hours; Refrigerated: 1 week; Frozen: 1 month
Methodology
Polymerase Chain Reaction (PCR)/Fluorescence Monitoring
Performed
Varies
Reported
5-10 days
Reference Interval
By report
Interpretive Data
Refer to report
Compliance Category
Laboratory Developed Test (LDT)
Note
Hotline History
Hotline History
Date of Change
Test Name Change
Methodology
Performance/Reported Schedule
Specimen Requirements
Reference Interval
Interpretive Data
Note
CPT Code
Component Change
Other Interface Change
New Test
Inactive
N/A
CPT Codes
81225
Components
| Component Test Code* | Component Chart Name | LOINC |
|---|---|---|
| 2008936 | CYP2C19 Phenotype | 79714-2 |
| 3001509 | 2C19GENO Specimen | 31208-2 |
| 3001510 | CYP2C19 Genotype | 57132-3 |
| 3001511 | 2C19GENO Interpretation | 50398-7 |
| 3016869 | EER CYP2C19 | 11526-1 |
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
- 2C19
- CYP2C19
- Cytochrome P450 2C19 Genotype
- clopidogrel
- antidepressants
- voriconazole
- protein pump inhibitors
- omeprazole
- PPIs
- sertraline
- doxepine
- clomipramine
- imipramine
- SSRI
- TCA
- dexlansoprazole
- rabeprazole
- amitriptyline
- Plavix
- lansoprazole
- pantoprazole
- trimipramine
- escitalopram
CYP2C19
