Ordering Recommendation

Noninvasive assessment of liver fibrosis in patients with chronic viral hepatitis B or C (with or without HIV coinfection) and in patients with hepatic steatosis. Test can be performed only if the patient has a FibroScan score. Result based on both a panel of serum biomarkers (FibroMeter) and the FibroScan Vibration Controlled Transient Elastography (VCTE), a noninvasive, diagnostic ultrasound-based test that measures liver fibrosis.


Quantitative Nephelometry/Quantitative Enzymatic/Quantitative Spectrophotometry/Automated Cell Count/Electromagnetic Mechanical Clot Detection/Vibration Controlled Transient Elastography


Tue, Thu


1-5 days

New York DOH Approval Status
This test is New York DOH approved.
Specimen Required
Patient Preparation

Patient must be 18 years of age or older. Platelet count should be performed on the EDTA whole blood sample at the client site within 3 days of submission for testing.


Lavender (K2EDTA) or Pink (K2EDTA) AND Serum Separator Tube (SST) AND Light Blue (Sodium Citrate).

Specimen Preparation

Separate from cells ASAP or within 2 hours of collection. Transport 3 mL serum in an ARUP Standard Transport Tube. (Min: 1.2 mL) AND Transport 1 mL platelet-poor citrated plasma in an ARUP Standard Transport Tube. (Min: 0.5 mL) Do not send the EDTA whole blood to ARUP.

Storage/Transport Temperature

Serum: Frozen.
Plasma (citrated): CRITICAL FROZEN. Separate specimens must be submitted when multiple tests are ordered.

Unacceptable Conditions

All required specimens not received. No platelet count received. VCTE performance date greater than 6 months from the specimen draw date and time. Hemolyzed specimens.


Include an automated platelet count. The Liver Stiffness result (in kPa) from the Fibroscan VCTE must be submitted with the samples. The performance date of the VCTE must also be submitted.


Serum: Ambient: 8 hours; Refrigerated: 1 week; Frozen: 2 weeks
Plasma: Ambient: 24 hours; Refrigerated: Unacceptable; Frozen: 2 weeks

Reference Interval

By report

Interpretive Data

Refer to report.

Compliance Category

Laboratory Developed Test (LDT)


Delays in test performance may result if the VCTE result and date of performance is not included with the requisition.

Hotline History
CPT Codes

83883; 84450; 82977 (Alt code: 81599)

Component Test Code* Component Chart Name LOINC
2005664 FibroMeter Platelet Count 26515-7
2005666 Fibrometer Prothrombin Index 6302-4
2010928 Aspartate Aminotransferase, FibroMeter 1920-8
2010930 Gamma Glutamyl Transferase, FibroMeter 2324-2
2010932 Alpha-2-Macroglobulin, FibroMeter 1835-8
3001380 EER Fibrometer VCTE Report 11526-1
3001381 FibroMeter VCTE Metavir Classification 48794-2
3001382 FibroMeter VCTE Interpretation 48767-8
3001383 FibroScan VCTE Liver Stiffness 77615-3
3001384 FibroMeter VCTE Score 77616-1
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
  • FibroSure
Liver Fibrosis - FibroMeter Vibration Controlled Transient Elastography (FibroMeter plus FibroScan VCTE)