Aid in prognostication and therapeutic decisions for neoplasms where amplification has been demonstrated. Screening test for MET gene amplification.
Fluorescence in situ Hybridization (FISH)
Formalin fix (10 percent neutral buffered formalin) and paraffin embed tumor tissue. Transport tissue block or 4 unstained, consecutively cut, 5-micron thick sections, mounted on positively charged glass slides. (Min: 4 slides) Protect paraffin block and/or slides from excessive heat.
Room temperature. Also acceptable: Refrigerated.
Specimens fixed or processed in alternative fixatives (alcohol, Prefer) or heavy metal fixatives (B-4 or B-5). No tumor in tissue. Decalcified specimens.
Include surgical pathology report with reason for referral. The laboratory will not reject specimens that arrive without a pathology report but will hold the specimen until this information is received.
Ambient: Indefinitely; Refrigerated: Indefinitely; Frozen: Unacceptable
Refer to report.
Analyte Specific Reagent (ASR)
|Component Test Code*||Component Chart Name||LOINC|
|3000689||MET FISH Reference Number|
|3000690||MET FISH Source|
|3000691||MET/CEP7 FISH Ratio|
|3000692||Average MET Signal Number per Cell|
|3000693||Average CEP7 Signal Number per Cell|
|3000694||MET FISH Result|
|3002947||Total Cell Count||78236-7|