Ordering Recommendation

Use in conjunction with histologic and clinical information for the diagnosis of round cell/myxoid liposarcoma.

Mnemonic
DDIT3 FISH
Methodology

Fluorescence in situ Hybridization (FISH)

Performed

Monday-Friday

Reported

3-7 days

New York DOH Approval Status
This test is New York DOH approved.
Specimen Required
Patient Preparation
Collect

Tumor tissue.

Specimen Preparation

Formalin fix (10 percent neutral buffered formalin) and paraffin embed tissue. Protect paraffin block from excessive heat.  Transport tissue block or 5 unstained (4-micron thick sections) positively charged slides in a tissue transport kit (ARUP supply #47808) available online through eSupply using ARUP Connect™or contact ARUP Client Services at (800) 522-2787 (kit recommended but not required). (Min 2 slides).

Storage/Transport Temperature

Room temperature. Also acceptable: Refrigerated. Ship in cooled container during summer months.

Unacceptable Conditions

Specimens fixed or processed in alternative fixatives (alcohol, Prefer) or heavy metal fixatives (B-4 or B-5). No tumor in tissue. Decalcified specimens.

Remarks

Include surgical pathology report.

Stability

Ambient: Indefinitely; Refrigerated: Indefinitely; Frozen: Unacceptable

Reference Interval

By report

Interpretive Data

Refer to report. 

Compliance Category

Analyte Specific Reagent (ASR)

Note
Hotline History
N/A
CPT Codes

88366

Components
Component Test Code* Component Chart Name LOINC
3000635 DDIT3 FISH Reference Number
3000636 DDIT3 FISH Source
3000637 DDIT3 FISH Result
3000703 Scoring Method 81304-8
3002938 Total Cell Count 78236-7
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • CHOP break apart FISH
  • CHOP rearrangement FISH
  • DDIT3 break-apart FISH
  • DDIT3 FISH probe
  • DDIT3 rearrangement FISH
  • t(12;16) translocation by FISH
  • t(12;22)translocation by FISH
DDIT3 (CHOP) (12q13) Gene Rearrangement by FISH