Facilitates diagnosis of Burkitts lymphoma (BL) and B-cell lymphoma with features intermediate between BL and diffuse large B-cell lymphoma (DLBCL). Detects all MYC rearrangements, including t(8;14), t(2;8), and t(8;22).
Fluorescence in situ Hybridization (FISH)
Formalin fix (10 percent neutral buffered formalin) and paraffin-embed specimen. Protect paraffin block from excessive heat. Transport tissue block or 5 unstained (3-micron thick sections) positively charged slides in a tissue transport kit (ARUP supply #47808) available online through eSupply using ARUP Connect ™ or contact ARUP Client Services at (800) 522-2787 (kit is recommended but not necessary). (Min: 2 slides)
Room temperature or refrigerated. Ship in cooled container during summer months.
Specimens fixed or processed in alternative fixatives (alcohol, Prefer) or heavy metal fixatives (B-4 or B-5). No tumor in tissue. Decalcified specimens.
Include surgical pathology report.
Ambient: Indefinitely; Refrigerated: Indefinitely; Frozen: Unacceptable
Refer to report.
Analyte Specific Reagent (ASR)
|Component Test Code*||Component Chart Name||LOINC|
|3000616||MYC FISH Reference Number|
|3000617||MYC FISH Source|
|3000618||MYC FISH Result|
|3002948||Total Cell Count||78236-7|
- 8q24 gene rearrangement FISH
- Burkitt's Lymphoma
- LSI MYC FISH
- MYC FISH
- MYC gene rearrangement FISH