3001255
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Prion Markers (CJD), CSF

14-3-3 TAU
Example Reports
Negative
Positive

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NPDPSC Test Request Form for 14-3-3 Testing

Ordering Recommendation

May aid in the diagnosis of Creutzfeldt-Jakob disease (CJD). This test uses qualitative real-time quaking-induced conversion to identify the causative agent of CJD, and also includes indirect markers of neurodegenerative disease. 

New York DOH Approval Status

This test is New York state approved.

Specimen Required

Patient Preparation

Patient must be 12 years of age or older.

Collect

CSF

Specimen Preparation

The first 2 mL of CSF that flows from the tap should be discarded. Transfer 2 mL CSF to ARUP standard transport tubes or other polypropylene tubes, taking care to avoid blood contamination from the tap, and freeze immediately. (Min: 1 mL)
Test is not performed at ARUP; separate specimens must be submitted when multiple tests are ordered.

Storage/Transport Temperature

CRITICAL FROZEN

Unacceptable Conditions
Remarks

Completed requisition form required. Cloudy or pink specimens may result in partial results for some components.

Stability

Ambient: Unacceptable; Refrigerated: Unacceptable; Frozen: Indefinitely

Methodology

Quantitative Enzyme-Linked Immunosorbent Assay (ELISA)/Qualitative Real-Time Quaking-Induced Conversion

Performed

Varies

Reported

7-17 days

Reference Interval

By report

Interpretive Data



Compliance Category

Performed by non-ARUP Laboratory

Note

Repeat testing should be collected no sooner than 2 weeks following last encounter.

Hotline History

View Hotline History

 

Hotline History

Date of Change
Test Name Change
Methodology
Performance/Reported Schedule
Specimen Requirements
Reference Interval
Interpretive Data
Note
CPT Code
Component Change
Other Interface Change
New Test
Inactive
01/02/2024
X
X
X
08/07/2023
X
X
X
X
N/A

CPT Codes

86317; 0035U

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Components

Component Test Code* Component Chart Name LOINC
3001256 Prion Markers (CJD), CSF 19146-0
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.

Aliases

  • 14-3-3 Protein Tau, Total, CSF
  • Creutzfeldt-Jakob Disease
  • Human Prion Disease
  • RT QuIC
Prion Markers (CJD), CSF

NPDPSC