Ordering Recommendation

HIV-1 phenotyping to determines tropism (CCR5 or CXCR4) of HIV-1 virus in patients being considered for CCR5 antagonist therapy.

Mnemonic
HIV TROFIL
Methodology

Recombinant virus, single replication

Performed

Varies

Reported

16-23 days
N/A

New York DOH Approval Status
This test is New York DOH approved.
Specimen Required
Patient Preparation
Collect

Lavender (K2EDTA) or Plasma Preparation Tube (PPT).

Specimen Preparation

Separate from cells within 6 hours of collection. Transfer 3 mL plasma to an ARUP Standard Transport Tube and freeze immediately. (Min: 3 mL)

Storage/Transport Temperature

CRITICAL FROZEN. Separate specimens must be submitted when multiple tests are ordered.

Unacceptable Conditions

Thawed specimens.

Remarks
Stability

Ambient: Unacceptable; Refrigerated: Unacceptable; Frozen: 2 weeks

Reference Interval
Interpretive Data



Compliance Category

Performed by non-ARUP Laboratory

Note

Procedure should be used for patients with documented HIV-1 infection and viral loads greater than 1000 copies/mL.

Hotline History
N/A
CPT Codes

87999

Components
Component Test Code* Component Chart Name LOINC
3001247 EER Trofile Coreceptor Tropism 51969-4
3001248 Trofile Coreceptor Tropism 57182-8
3001249 Trofile Coreceptor Tropism, Tropotype 51969-4
3001250 Trofile Coreceptor Tropism, Interp 77202-0
3001251 Trofile Coreceptor Tropism, Methodology 49549-9
3001252 Trofile Coreceptor Tropism, References 75608-0
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • CCR5
  • Chemokine Coreceptor Tropism Trofile
  • CXCR4
Human Immunodeficiency Virus Type 1 (HIV-1) Trofile Co-Receptor Tropism

Monogram Biosciences