Ordering Recommendation

Intended for use in patients with viral loads ≥1,000 copies/mL. HIV-1 phenotyping test to determine the tropism (ie, CCR5 or CXCR4) of the virus in patients being considered for CCR5 antagonist therapy.


Polymerase Chain Reaction/Culture




27-38 days

New York DOH Approval Status

This test is New York DOH approved.

Specimen Required

Patient Preparation

Lavender (K2EDTA) or Plasma Preparation Tube (PPT).

Specimen Preparation

Separate from cells within 6 hours of collection. Transfer 3 mL plasma to an ARUP Standard Transport Tube and freeze immediately. (Min: 3 mL)

Storage/Transport Temperature

CRITICAL FROZEN. Separate specimens must be submitted when multiple tests are ordered.

Unacceptable Conditions

Thawed specimens.


Ambient: Unacceptable; Refrigerated: Unacceptable; Frozen: 2 weeks

Reference Interval

Interpretive Data

Compliance Category

Performed by non-ARUP Laboratory


Procedure should be used for patients with documented HIV-1 infection and viral loads greater than 1000 copies/mL.

Hotline History


CPT Codes



Component Test Code* Component Chart Name LOINC
3001247 EER Trofile Coreceptor Tropism 51969-4
3001248 Trofile Coreceptor Tropism 57182-8
3001249 Trofile Coreceptor Tropism, Tropotype 51969-4
3001250 Trofile Coreceptor Tropism, Interp 77202-0
3001251 Trofile Coreceptor Tropism, Methodology 49549-9
3001252 Trofile Coreceptor Tropism, References 75608-0
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.


  • CCR5
  • Chemokine Coreceptor Tropism Trofile
  • CXCR4
Human Immunodeficiency Virus Type 1 (HIV-1) Trofile Co-Receptor Tropism

Monogram Biosciences