Recommended testing for HCV genotype 1 patients prior to initiating simeprevir therapy. Identifies the Q80K polymorphism.
Polymerase Chain Reaction/Sequencing
Lavender (EDTA) or Plasma Preparation Tube (PPT).
Separate from cells within 6 hours of collection. Transfer 3 mL plasma to an ARUP Standard Transport Tube and freeze immediately. (Min: 3 mL)
CRITICAL FROZEN. Separate specimens must be submitted when multiple tests are ordered.
Ambient: Unacceptable; Refrigerated: Unacceptable; Frozen: 2 weeks
Performed by non-ARUP Laboratory
Procedure should be used for patients with HCV genotype (subtype) 1a or 1b and a viral load greater than 2000 IU/mL.
|Component Test Code*||Component Chart Name||LOINC|
|3001235||EER HCV GenoSure NS3 and NS4A||32286-7|
|3001236||HCV GenoSure NS3 and NS4A||32286-7|
|3001237||HCV GenoSure NS3 and NS4A Interpretation||77202-0|
- HCV Drug Resistance
- NS3/4 Resistance Analysis
- Q80K Polymorphism