Ordering Recommendation

HIV-1 combined pheno- and genotyping test provides antiretroviral susceptibility information for protease inhibitors (PI), reverse transcriptase inhibitors (NRTI, NNRTI), and integrase inhibitors (INI). Preferred test for patients with known or suspected complex drug resistance patterns (eg, suboptimal virologic response to treatment and viral load rebound).

Mnemonic
HIVPS PLUS
Methodology

Phenotyping/Genotyping

Performed

Varies

Reported

19-26 days

New York DOH Approval Status
This test is New York DOH approved.
Specimen Required
Patient Preparation
Collect

Lavender (EDTA) or plasma preparation tube (PPT).

Specimen Preparation

Separate from cells within 6 hours of collection. Transfer 5 mL plasma to ARUP Standard Transport Tubes and freeze immediately. (Min: 3 mL)

Storage/Transport Temperature

CRITICAL FROZEN. Separate specimens must be submitted when multiple tests are ordered.

Unacceptable Conditions

Thawed specimens.

Remarks
Stability

Ambient: Unacceptable; Refrigerated: Unacceptable; Frozen: 2 weeks

Reference Interval

By report

Interpretive Data



Compliance Category

Performed by non-ARUP Laboratory

Note

Procedure should be used for patients with documented HIV-1 infection and viral loads greater than 500 copies/mL.

Hotline History
N/A
CPT Codes

87900; 87901; 87903; 87904 x14; 87906

Components
Component Test Code* Component Chart Name LOINC
3001187 EER HIV-1 PhenoSense GT + Integrase 51969-4
3001188 HIV-1 PSGT + Integrase, Net Assessment 83326-9
3001189 HIV-1 PSGT + Integrase, Phenotype 49665-3
3001190 HIV-1 PSGT + Integrase, Genotype
3001191 HIV-1 PSGT + Integrase, Interpretation 77202-0
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
Human Immunodeficiency Virus Type 1 (HIV-1) PhenoSense GT Plus Integrase

Monogram Biosciences