Ordering Recommendation

Aids in the diagnosis and management of acute myeloid leukemia. Not intended for minimal residual disease monitoring.

New York DOH Approval Status

This test is New York state approved.

Specimen Required

Patient Preparation
Collect

Whole blood or bone marrow in lavender (EDTA).
Also acceptable: Whole blood in green (sodium heparin).

Specimen Preparation

Whole Blood: Do not freeze. Transport 5 mL whole blood. (Min: 1 mL)
Bone Marrow: Do not freeze. Transport 3 mL bone marrow. (Min: 1 mL)

Storage/Transport Temperature

Refrigerated.

Unacceptable Conditions

Plasma, serum, FFPE tissue blocks/slides, or frozen tissue. Specimens collected in anticoagulants other than EDTA. Clotted or grossly hemolyzed specimens.

Remarks
Stability

Refrigerated: 7 days; Frozen: Unacceptable

Methodology

Capillary Electrophoresis

Performed

Varies

Reported

2-7 days

Reference Interval

Interpretive Data

Refer to report.

Compliance Category

Laboratory Developed Test (LDT)

Note

Hotline History

N/A

CPT Codes

81245; 81246

Components

Component Test Code* Component Chart Name LOINC
3001162 FLT3 Source 31208-2
3001163 ITD Result 79210-1
3001164 ITD Ratio 92844-0
3001165 TKD Result 69548-6
3001166 FLT3 ITD and TKD Mutation Detection 50398-7
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.

Aliases

  • FLT3 CDX
  • FLT3 D835
  • FLT3 ITD
  • FLT3 Mutant
  • FLT3 Ratio
  • FLT3 Signal Ratio
  • FLT3 TKD
FLT3 ITD and TKD Mutation Detection