FLT3 ITD and TKD Mutation Detection

3001161
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Example Reports
Detected
Not Detected
Ordering Recommendation

Aid in the diagnosis and management of acute myeloid leukemia. Not intended for minimal residual disease monitoring.

Mnemonic
FLT3-PCR
Methodology

Polymerase Chain Reaction

Performed

DNA isolation: Sun-Sat
Assay: Mon-Sat

Reported

2-7 days

New York DOH Approval Status
This test is New York DOH approved.
Specimen Required
Patient Preparation
Collect

Lavender (EDTA) or bone marrow (EDTA). Also acceptable: DNA extracted by CLIA certified lab.

Specimen Preparation

Whole Blood: Do not freeze. Transport 5 mL whole blood. (Min: 1 mL)
Bone Marrow: Do not freeze. Transport 3 mL bone marrow. (Min: 1 mL)
Extracted DNA: Transport 40 uL DNA with at least 50 ng/uL concentration. (Min: 40 uL) Transport DNA in a tissue transport kit (ARUP Supply #47808) available online through eSupply using ARUP Connect™ or contact ARUP Client Services at (800) 522-2787.

Storage/Transport Temperature

Refrigerated.

Unacceptable Conditions

Plasma, serum, FFPE tissue blocks/slides, or frozen tissue, DNA extracted by a non-CLIA lab. Specimens collected in anticoagulants other than EDTA or sodium heparin. Clotted or grossly hemolyzed specimens.

Remarks
Stability

Ambient: 24 hours; Refrigerated: 5 days; Frozen: Unacceptable
Extracted DNA: Ambient: 1 month; Refrigerate: Indefinitely; Frozen: Indefinitely

Reference Interval
Interpretive Data

Refer to report. 

Compliance Statement B: For laboratory developed tests not using a RUO kit, and for FDA approved, cleared or 510(k) exempt assays with alterations. This test was developed and its performance characteristics determined by ARUP Laboratories. The U. S. Food and Drug Administration has not approved or cleared this test; however, FDA clearance or approval is not currently required for clinical use. The results are not intended to be used as the sole means for clinical diagnosis or patient management decisions.

Note
Hotline History

View Hotline History

 

Hotline History

Date of Change
Test Name Change
Methodology
Performance/Reported Schedule
Specimen Requirements
Reference Interval
Interpretive Data
Note
CPT Code
Component Change
Other Interface Change
New Test
Inactive
08/19/2019
X
12/11/2018
X
N/A
CPT Codes

81245; 81246

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Components
Component Test Code* Component Chart Name LOINC
3001162 FLT3 Source 31208-2
3001163 ITD Result 79210-1
3001164 ITD Ratio 92844-0
3001165 TKD Result 69548-6
3001166 FLT3 ITD and TKD Mutation Detection 50398-7
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • FLT3 CDX
  • FLT3 D835
  • FLT3 ITD
  • FLT3 Mutant
  • FLT3 Ratio
  • FLT3 Signal Ratio
  • FLT3 TKD
FLT3 ITD and TKD Mutation Detection