Ordering Recommendation

Panel to evaluate kidney function.

Mnemonic
KID PRO
Methodology

Quantitative Immunoturbidimetry/Quantitative Enzymatic/Quantitative Spectrophotometry

Performed

Sun-Sat

Reported

Within 24 hours

New York DOH Approval Status
Specimens from New York clients will be sent out to a New York DOH approved laboratory, if possible.
Specimen Required
Patient Preparation
Collect

Plasma Separator Tube (PST) or Serum Separator Tube (SST) AND random urine. Also acceptable: 24 hour urine.

Specimen Preparation

Allow serum tube to clot completely at room temperature. Separate from cells ASAP or within 2 hours. Transfer 1 mL serum or plasma to an ARUP Standard Transport Tube. (Min: 0.2 mL) AND Transfer one 3 mL aliquot of urine to an ARUP Standard Transport Tube. (Min: 0.5 mL) Also acceptable: Urine specimens previously preserved with 6M HCl, boric acid, or 5 percent NaOH.

Storage/Transport Temperature

Refrigerated.

Unacceptable Conditions

Specimens obtained through catheters, used to infuse hyperalimentation fluid. Specimens with potassium oxalate/sodium fluoride, citrate, or EDTA as anticoagulants.

Remarks

Patient age and sex are required for calculation.

Stability

Ambient: 48 hours; Refrigerated: 1 week; Frozen: 3 months

Reference Interval

By report

Interpretive Data

The CKD-EPI equation for non-African American individuals is used to calculate the estimated glomerular filtration rate (GFR). To estimate the GFR for African Americans, multiply the provided GFR result by 1.16.

The CKD-EPI equation is validated in individuals 18 years of age and older. However, the equation is less accurate in patients with extremes of muscle mass, restriction of dietary protein, ingestion of creatine, extra-renal metabolism of creatinine, or treatment with medications that affect renal tubular creatinine secretion.


GFR Categories in Chronic Kidney Disease (CKD)
GFR Category
GFR (mL/min/1.73 square meters)
Interpretation
G1 90 or greater Normal or high*
G2 60-89 Mild decrease*
G3a 45-59 Mild to moderate decrease
G3b 30-44 Moderate to severe decrease
G4 15-29 Severe decrease
G5 14 or less Kidney failure
*In the absence of evidence of kidney damage, neither GFR category G1 nor G2 fulfill the criteria for CKD (Kidney Int Suppl 2013;3:1-150)

No compliance statements are in use for this test.

Note

If a 24-hour urine collection is submitted, 24-hour calculations will not be performed. If 24-hour calculations are required, refer to test code 0050203 Albumin-Creatinine Ratio, Urine.

Hotline History
N/A
CPT Codes

82043; 82570; 82565

Components
Component Test Code* Component Chart Name LOINC
0020025 Creatinine, Serum or Plasma 2160-0
0020207 Creatinine, Urine - per volume 2161-8
0026634 Calculated GFR 62238-1
0050583 Albumin - mg/dL 30003-8
0050678 Albumin/Creatinine Ratio 14958-3
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
Kidney Profile