Ordering Recommendation

For the direct detection and identification of fungi in tissue.

New York DOH Approval Status

This test is not New York state approved. There are no New York state-approved laboratories available. Submit a Non-Permitted Laboratory Request Form (NPL) to the NYDOH prior to collection of specimen. If NPL is approved by NYDOH, and sample is received at ARUP, testing will be performed.

Specimen Required

Patient Preparation
Collect

Tissue.

Specimen Preparation

Transfer fresh tissue to a sterile container and freeze immediately. (Min: 25 mg) Also acceptable: Formalin-fixed paraffin-embedded (FFPE) tissue. (Min: 3 10-micron thick sections).

Storage/Transport Temperature

 Fresh Tissue: Frozen. FFPE: Room temperature.

Unacceptable Conditions

Finger nails, toe nails, or bone. Formalin-fixed paraffin-embedded tissue on slides.

Remarks
Stability

Fresh Tissue: Ambient: 5 days; Refrigerated: 5 days; Frozen: 5 days
FFPE:
Ambient: 1 month; Refrigerated: 1 month; Frozen: Unacceptable

Methodology

Polymerase Chain Reaction/Sequencing

Performed

Sun, Mon, Wed

Reported

3-5 days

Reference Interval

Interpretive Data

This assay detects and identifies human fungal pathogens by Sanger sequencing. This assay cannot differentiate invasive fungal infection from environmental fungal DNA. Clinical correlation of sequencing result is recommended.

This test was developed and its performance characteristics determined by ARUP Laboratories. It has not been cleared or approved by the US Food and Drug Administration. This test was performed in a CLIA certified laboratory and is intended for clinical purposes.

Compliance Category

Laboratory Developed Test (LDT)

Note

Hotline History

N/A

CPT Codes

87999

Components

Component Test Code* Component Chart Name LOINC
3000497 PanFungal Identification by Sequencing 48767-8
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.

Aliases

PanFungal Identification by Sequencing