Search our extensive Laboratory Test Directory to find test codes, ordering recommendations, specimen stability information, Test Fact Sheets, and more.
Recommendations when to order or not order the test. May include related or preferred tests.
Useful for confirming a diagnosis of systemic lupus erythematosus (SLE) or mixed connective tissue disease (MCTD) following a positive ANA result. Antibodies may be useful in the differential diagnosis of other systemic autoimmune rheumatic diseases such as systemic sclerosis, Sjögren syndrome, polymyositis, dermatomyositis, and overlap syndromes.
New York DOH Approval Status
Indicates whether a test has been approved by the New York State Department of Health.
This test is New York state approved.
Specimen Required
Patient PreparationInstructions patient must follow before/during specimen collection.
CollectSpecimen type to collect. May include collection media, tubes, kits, etc.
Serum Separator Tube (SST).
Specimen PreparationInstructions for specimen prep before/after collection and prior to transport.
Separate from cells ASAP or within 2 hours of collection. Transfer 1 mL serum to an ARUP Standard Transport Tube. (Min: 0.2 mL)
Storage/Transport TemperaturePreferred temperatures for storage prior to and during shipping to ARUP. See Stability for additional info.
Refrigerated.
Unacceptable ConditionsCommon conditions under which a specimen will be rejected.
Plasma or other body fluids. Contaminated, hemolyzed, or severely lipemic specimens.
RemarksAdditional specimen collection, transport, or test submission information.
StabilityAcceptable times/temperatures for specimens. Times include storage and transport time to ARUP.
After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 month (avoid repeated freeze/thaw cycles)
Expected turnaround time for a result, beginning when ARUP has received the specimen.
1-3 days
Reference Interval
Normal range/expected value(s) for a specific disease state. May also include abnormal ranges.
Test Number
Components
Reference Interval
Smith/RNP (ENA) Ab, IgG
19 Units or less
Smith (ENA) Antibody, IgG
40 AU/mL or less
Interpretive Data
May include disease information, patient result explanation, recommendations, or details of testing.
Components
Interpretation
Smith/RNP (ENA) Antibody, IgG
19 Units or less: Negative 20-39 Units: Weak Positive 40-80 Units: Moderate Positive 81 Units or greater: Strong Positive
Smith (ENA) Antibody, IgG
29 AU/mL or less: Negative 30-40 AU/mL: Equivocal 41 AU/mL or greater: Positive
Compliance Category
FDA
Note
Additional information related to the test.
Hotline History
N/A
CPT Codes
The American Medical Association Current Procedural Terminology (CPT) codes published in ARUP's Laboratory Test Directory are provided for informational purposes only. The codes reflect our interpretation of CPT coding requirements based upon AMA guidelines published annually. CPT codes are provided only as guidance to assist clients with billing. ARUP strongly recommends that clients confirm CPT codes with their Medicare administrative contractor, as requirements may differ. CPT coding is the sole responsibility of the billing party. ARUP Laboratories assumes no responsibility for billing errors due to reliance on the CPT codes published.
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
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