Ordering Recommendation

Reflexive panel to assist in diagnosis of thrombotic thrombocytopenic purpura (TTP) and in distinguishing between inherited and acquired forms of TTP.  

Mnemonic
ADAMTS PAN
Methodology

Quantitative Enzyme-Linked Immunosorbent Assay

Performed

Tue

Reported

1-8 days

New York DOH Approval Status
Specimens from New York clients will be sent out to a New York DOH approved laboratory, if possible.
Specimen Required
Patient Preparation
Collect

Light Blue (Sodium Citrate). Refer to Specimen Handling at aruplab.com for hemostasis/thrombosis specimen handling guidelines.

Specimen Preparation

Transfer 3 mL platelet-poor plasma to an ARUP Standard Transport Tube. (Min: 2 mL)

Storage/Transport Temperature

CRITICAL FROZEN. Separate specimens must be submitted when multiple tests are ordered.

Unacceptable Conditions

Serum, or EDTA plasma. Clotted or hemolyzed specimens.

Remarks
Stability

Ambient: 2 hours; Refrigerated: Unacceptable; Frozen: 2 weeks (No freeze/thaw cycles.)

Reference Interval
Test Number
Components
Reference Interval
0030056 ADAMTS13 Activity Effective November 17, 2014

Greater than 60 percent

Interpretive Data

Refer to report.

Compliance Statement D: For laboratory tests using a manufactured RUO kit. This test was developed and its performance characteristics determined by ARUP Laboratories. The U. S. Food and Drug Administration has not approved or cleared this test; however, FDA clearance or approval is not currently required for clinical use. The results are not intended to be used as the sole means for clinical diagnosis or patient management decisions.

Note

If ADAMTS13 Activity is less than or equal to 30 percent, then ADAMTS13 Inhibitor will be added. If ADAMTS13 Inhibitor is less than 0.8 BU, then ADAMTS13 Antibody will be added. Additional charges apply.

Hotline History
N/A
CPT Codes

85397, if reflexed, add, 85335, if reflexed, add 83520

Components
Component Test Code* Component Chart Name LOINC
0030049 ADAMTS13 Activity 53622-7
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
ADAMTS13 Reflex Panel