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Fungal Antibodies with Reflex to Blastomyces dermatitidis Antibodies by Immunodiffusion, CSF

FUNG R CSF
Example Reports
Negative
Positive

Ordering Recommendation

Not recommended for the diagnosis of fungal infection of the central nervous system. Includes testing by complement fixation for Aspergillus, Coccidioides, and Histoplasma and testing by immunoassay for Blastomyces. Refer to individual fungus-specific testing according to patient exposure.

New York DOH Approval Status

This test is not New York state approved. There are no New York state-approved laboratories available. Submit a Non-Permitted Laboratory Request Form (NPL) to the NYDOH prior to collection of specimen. If NPL is approved by NYDOH, and sample is received at ARUP, testing will be performed.

Specimen Required

Patient Preparation
Collect

CSF.

Specimen Preparation

Transfer 2 mL CSF to an ARUP standard transport tube. (Min: 1 mL)

Storage/Transport Temperature

Refrigerated.

Unacceptable Conditions

Other body fluids. Contaminated, hemolyzed, xanthochromic, or severely lipemic specimens.

Remarks
Stability

Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles)

Methodology

Semi-Quantitative Complement Fixation/Semi-Quantitative Enzyme-Linked Immunosorbent Assay (ELISA)/Qualitative Immunodiffusion

Performed

Sun-Sat

Reported

2-6 days

Reference Interval

Test Number
 Components
 Reference Interval
  Coccidioides Ab by CF, CSF Less than 1:2
  Aspergillus Antibody, CSF (CF) Less than 1:2
  Histoplasma M, CSF (CF) Less than 1:2
  Histoplasma Y, CSF (CF) Less than 1:2
  Blastomyces Antibodies EIA, CSF 0.9 IV or less

Interpretive Data

Refer to report.

Compliance Category

Modified FDA

Note

This test detects antibodies to Aspergillus, Coccidioides, and Histoplasma by complement fixation and Blastomyces by immunoassay.
If Blastomyces antibodies are equivocal or positive by immunoassay then Blastomyces dermatitidis Antibodies by Immunodiffusion, CSF will be added. Additional charges apply.

Hotline History

View Hotline History

 

Hotline History

Date of Change
Test Name Change
Methodology
Performance/Reported Schedule
Specimen Requirements
Reference Interval
Interpretive Data
Note
CPT Code
Component Change
Other Interface Change
New Test
Inactive
05/15/2023
X
X
N/A

CPT Codes

86606; 86612; 86635; 86698 x2; if reflexed, add 86612

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Components

Component Test Code* Component Chart Name LOINC
0050711 Coccidioides Ab by CF, CSF 13917-0
0050751 Aspergillus Antibody, CSF (CF) 23953-3
0050753 Histoplasma M, CSF (CF) 27220-3
0050754 Histoplasma Y, CSF (CF) 27209-6
3000233 Blastomyces Antibodies EIA, CSF 13201-9
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.

Aliases

  • Aspergillus
  • Blastomyces
  • Coccidiodes
  • fungal meningitis
  • Histoplasma
Fungal Antibodies with Reflex to Blastomyces dermatitidis Antibodies by Immunodiffusion, CSF