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Alpha Fetoprotein (Amniotic Fluid) with Reflex to Acetylcholinesterase and Fetal Hemoglobin
Ordering Recommendation
Evaluate possibility of a fetal open neural tube defect at 13-36 weeks of gestation.
Methodology
Quantitative Chemiluminescent Immunoassay/Electrophoresis
Performed
Sun-Sat
Reported
3-4 days
Reflex: 3-11 days
New York DOH Approval Status
Specimen Required
Amniocentesis. Specimen must be drawn between 13 weeks, 0 days and 36 weeks, 6 days gestation.
Amniotic fluid.
Transport 2.5 mL amniotic fluid. (Min: 1.5 mL)
Room temperature.
Submit with Order: Gestational age at time of collection or estimated due date.
Ambient: 1 month; Refrigerated: 3 months; Frozen: 3 months
Reference Interval
| Test Number |
Components |
Reference Interval |
|---|---|---|
| AFP, AF MoM | ≤1.99 |
Interpretive Data
Refer to report.
This test was developed and its performance characteristics determined by ARUP Laboratories. It has not been cleared or approved by the US Food and Drug Administration. This test was performed in a CLIA certified laboratory and is intended for clinical purposes.
Modified FDA
Note
Information must include weeks of gestation. If the AFP (amniotic fluid) is elevated, then Acetylcholinesterase will be added. Additional charges apply. Acetylcholinesterase testing requires an additional 3-11 days to be reported.
Hotline History
CPT Codes
82106; if reflexed, add 82013 and 83033
Components
| Component Test Code* | Component Chart Name | LOINC |
|---|---|---|
| 0080015 | AFP, Amniotic Fluid | 1832-5 |
| 0080929 | AFP AF Interpretation | 41273-4 |
| 3000162 | AFP, AF MoM | 29595-6 |
| 3000263 | Gestational Age Calculated at Collection | 18185-9 |
Aliases
- AFP
- AFP-AF (Alpha-Fetoprotein, Amniotic Fluid)
- Alpha Fetoprotein, Amniotic Fluid
- Alpha-Fetoprotein, Amniotic Fluid
- Fetoprotein, Amniotic Fluid
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