Ordering Recommendation

Diagnose relapsing fever caused by various Borrelia species during the symptomatic phase of infection.

New York DOH Approval Status

This test is New York state approved.

Specimen Required

Patient Preparation

Lavender (K2EDTA) or Pink (K2EDTA).

Specimen Preparation

Transport 1 mL whole blood. (Min: 0.5 mL)

Storage/Transport Temperature


Unacceptable Conditions

Serum or plasma. Heparinized specimens.


Specimen source required.


Ambient: 24 hours; Refrigerated: 5 days; Frozen: 1 week


Qualitative Polymerase Chain Reaction




1-3 days

Reference Interval

Interpretive Data

This test was developed and its performance characteristics determined by ARUP Laboratories. It has not been cleared or approved by the US Food and Drug Administration. This test was performed in a CLIA certified laboratory and is intended for clinical purposes.

Compliance Category

Laboratory Developed Test (LDT)


This test is designed to detect but not differentiate the nucleic acid from B. hermsii, B. miyamotoi, B. parkeri, and B. turicatae. Additional less-frequently encountered relapsing fever Borrelia species may also be detected, including  B. recurrentis, B. coriaceae, B. theileri, B. lonestari, and B. anserina. A result of "Detected" indicates the presence of nucleic acid from any one of these species in the specimen.

Hotline History


CPT Codes



Component Test Code* Component Chart Name LOINC
3000011 Relapsing Fever Borrelia Source 31208-2
3000012 Relapsing Fever Borrelia by PCR 96056-7
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.


  • Borrelia anserina
  • Borrelia coriaceae
  • Borrelia hermsii
  • Borrelia lonestari
  • Borrelia miyamotoi
  • Borrelia parkeri
  • Borrelia recurrentis
  • Borrelia theileri
  • Borrelia turicatae
  • Tick-Borne Relapsing Fever
Relapsing Fever Borrelia Species by PCR