Monitor engraftment of maternal T cells in patients with severe combined immunodeficiency (SCID) prior to allogenic stem cell transplantation.
Polymerase Chain Reaction/Fragment Analysis
New York DOH Approval Status
Lavender (EDTA), Pink (K2EDTA), or Yellow (ACD Solution A).
New York State Clients: Lavender (EDTA) or Yellow (ACD Solution A). Collect Monday-Thursday only.
Transport 2 mL whole blood. (Min: 1 mL)
New York State Clients: Transport 9 mL whole blood. (Min: 4 mL). Do not send to ARUP Laboratories. Specimens must be received at performing laboratory within 48 hours of collection. For specimen requirements and direct submission instructions please contact ARUP Referral Testing at (800) 242-2787, ext. 5145.
Room Temperature: 1 week; Refrigerated: 1 month; Frozen: unacceptable
New York State Clients: Room Temperature: 48 hours; Refrigerated: Unacceptable; Frozen: Unacceptable
Refer to report.
Laboratory Developed Test (LDT)
To complete Maternal T Cell Engraftment in SCID testing, samples should be collected to perform the following three tests: (1) A buccal swab or brush collected from the patient for Maternal T Cell Engraftment in SCID, Pre-Engraftment Specimen (ARUP test code 2014694), used as a genetic baseline for the patient. (2) A peripheral blood sample from the biological mother for Maternal T Cell Engraftment in SCID, Maternal Specimen (ARUP test code 2014704), used as a genetic baseline for the mother. (3) A peripheral blood sample collected from the patient for Maternal T Cell Engraftment in SCID, (ARUP test code 2014699). T cells isolated from the blood sample will be genotyped for comparison to the patient and biological mother baseline genotypes. If T cell sorting is not completed on the blood sample before submission, BMT Cell Isolation (ARUP test code 2005498) will be added. Additional charges apply.
See CPT code for Maternal T Cell Engraftment in SCID, Pre-Engraftment Specimen (ARUP test code 2014694)
|Component Test Code*||Component Chart Name||LOINC|
|2014705||Maternal Specimen, Maternal Engraftment|
|2014706||Maternal Engraftment, Informative Loci|
|2014707||Maternal Engraftment, Mat Spec Interp|
- Maternal cell engraftment
- Maternal engraftment
- SCID engraftment