2014699
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Maternal T Cell Engraftment in SCID

STR-SCID
Example Reports
Maternal
Mixed
Patient

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Time Sensitive

Ordering Recommendation

Use to monitor engraftment of maternal T cells in patients with severe combined immunodeficiency (SCID) prior to allogenic stem cell transplantation.

New York DOH Approval Status

This test is not New York state approved. There are no New York state-approved laboratories available. Submit a Non-Permitted Laboratory Request Form (NPL) to the NYDOH prior to collection of specimen. If NPL is approved by NYDOH, and sample is received at ARUP, testing will be performed.

Specimen Required

Patient Preparation
Collect

Lavender (EDTA), pink (K2EDTA), or yellow (ACD solution A)

Specimen Preparation

Transport 3 mL whole blood. (Min: 2 mL)

Storage/Transport Temperature

Preferred transport temp: Room temperature. Also acceptable: Refrigerated. Ship overnight. Specimens should be received within 24 hours of collection for optimal isolation of T cells.

Unacceptable Conditions

Frozen, clotted, or hemolyzed specimens.

Remarks
Stability

Room temperature: 3 days; Refrigerated: 3 days; Frozen: Unacceptable

Methodology

Polymerase Chain Reaction (PCR) / Fragment Analysis

Performed

Sun-Sat

Reported

5-9 days

Reference Interval

Type Maternal Maternal cells only.
Type Patient Patient cells only.
Mixed Patient and maternal T cells present. Semiquantitative results of percentage of patient and maternal cells will be reported.

Interpretive Data

Refer to report.

Compliance Category

Laboratory Developed Test (LDT)

Note

To complete Maternal T Cell Engraftment in SCID testing, samples should be collected to perform the following three tests: (1) A buccal brush collected from the patient for Maternal T Cell Engraftment in SCID, Pre-Engraftment Specimen (ARUP test code 2014694), used as a genetic baseline for the patient. (2) A peripheral blood sample from the biological mother for Maternal T Cell Engraftment in SCID, Maternal Specimen (ARUP test code 2014704), used as a genetic baseline for the mother. (3) A peripheral blood sample collected from the patient for Maternal T Cell Engraftment in SCID (ARUP test code 2014699). T cells isolated from the blood sample will be genotyped for comparison to the patient and biological mother baseline genotypes.

Hotline History

View Hotline History

 

Hotline History

Date of Change
Test Name Change
Methodology
Performance/Reported Schedule
Specimen Requirements
Reference Interval
Interpretive Data
Note
CPT Code
Component Change
Other Interface Change
New Test
Inactive
11/03/2025
X
08/04/2025
X
N/A

CPT Codes

81268; If cell sorting is performed, add 88184

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Components

Component Test Code* Component Chart Name LOINC
2014700 Specimen, Maternal Engraftment
2014701 Mat Engraftment, Informative Loci
2014702 Maternal Engraftment, Interpretation
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.

Aliases

  • Maternal engraftment
  • SCID engraftment
Maternal T Cell Engraftment in SCID