Ordering Recommendation

Monitor engraftment of maternal T cells in patients with severe combined immunodeficiency (SCID) prior to allogenic stem cell transplantation.




Polymerase Chain Reaction/Fragment Analysis




5-9 days

New York DOH Approval Status

Specimens from New York clients will be sent out to a New York DOH approved laboratory, if possible.

Specimen Required

Patient Preparation

Buccal swab or buccal brush.

Specimen Preparation

Collect 3-4 swab/brush samples from patient and place in dry, sterile container for transport.

Storage/Transport Temperature

Room temperature.

Unacceptable Conditions

Ambient: 1 week Refrigerated: 1 month; Frozen: Unacceptable

Reference Interval

By report

Interpretive Data

Refer to report.

This test was developed and its performance characteristics determined by ARUP Laboratories. It has not been cleared or approved by the US Food and Drug Administration. This test was performed in a CLIA certified laboratory and is intended for clinical purposes.

Compliance Category

Laboratory Developed Test (LDT)


To complete Maternal T Cell Engraftment in SCID testing, samples should be collected to perform the following three tests: (1) A buccal swab or brush collected from the patient for Maternal T Cell Engraftment in SCID, Pre-Engraftment Specimen (ARUP test code 2014694), used as a genetic baseline for the patient. (2) A peripheral blood sample from the biological mother for Maternal T Cell Engraftment in SCID, Maternal Specimen (ARUP test code 2014704), used as a genetic baseline for the mother. (3) A peripheral blood sample collected from the patient for Maternal T Cell Engraftment in SCID, (ARUP test code 2014699). T cells isolated from the blood sample will be genotyped for comparison to the patient and biological mother baseline genotypes. If T cell sorting is not completed on the blood sample before submission, BMT Cell Isolation (ARUP test code 2005498) will be added. Additional charges apply.

Hotline History


CPT Codes



Component Test Code* Component Chart Name LOINC
2014695 Specimen, Maternal Engraftment Pre
2014696 Maternal Engraftment, Pre Interp
2014697 Mat Engraftment, Pre, Informative Loci
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.


  • Maternal cell engraftment
  • Maternal engraftment
  • SCID
  • SCID engraftment
Maternal T Cell Engraftment in SCID, Pre-Engraftment Specimen