Hepatitis C Virus (HCV) Genotype with Reflex to HCV NS5A Drug Resistance by Sequencing
Order before initiating treatment with NS5A inhibitors. Use to determine HCV type 1-6 after molecular confirmation of positive HCV screen. If genotype “1a or 1b” is determined, testing will reflex to HCV NS5A for genotype differentiation and drug resistance by sequencing.
Polymerase Chain Reaction/Sequencing
Lavender (EDTA), Pink (K2EDTA), Plasma Preparation Tube (PPT), or Serum Separator Tube (SST).
Separate from cells ASAP or within 2 hours of collection. Transfer 2 mL serum or plasma to an ARUP Standard Transport Tube. (Min: 1.5 mL)
Ambient: Unacceptable; Refrigerated: 72 hours; Frozen: 4 months
Refer to report.
Laboratory Developed Test (LDT)
This test may be unsuccessful if the HCV RNA viral load is less than log 3.6 or 4000 IU/mL. If initial result is Type "1a or 1b", then HCV NS5A Drug Resistance by Sequencing will be added. Additional charges apply.
87902; if reflexed, add 87902
|Component Test Code*||Component Chart Name||LOINC|
|0055593||HCV Genotype by Sequencing||32286-7|