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Thiopurine Metabolites by LC-MS/MS
2014484
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Ordering Recommendation
Phenotype test used to optimize therapy for patients who are taking thiopurine drugs. Thiopurine metabolite concentrations are identified to assess therapeutic and toxic concentrations. If thiopurine therapy has not been initiated, order Thiopurine Methyltransferase, RBC (0092066).
Mnemonic
THIOPMETAB
Methodology
Quantitative Liquid Chromatography/Tandem Mass Spectrometry
Performed
Varies
Reported
3-5 days
New York DOH Approval Status
This test is New York DOH approved.
Specimen Required
Patient Preparation
Collect
Lavender (K2 or K3EDTA).
Specimen Preparation
Transport 3 mL whole blood. (Min: 1.5 mL)
Test is not performed at ARUP; separate specimens must be submitted when multiple tests are ordered.
Storage/Transport Temperature
Refrigerated.
Unacceptable Conditions
Hemolyzed specimens.
Remarks
Stability
Ambient: 24 hours; Refrigerated: 8 days; Frozen: Unacceptable
Reference Interval
By report
Interpretive Data
Compliance Category
Performed by non-ARUP Laboratory
Note
Hotline History
N/A
CPT Codes
80299
Components
| Component Test Code* | Component Chart Name | LOINC |
|---|---|---|
| 2014485 | 6-Thioguanine | 32660-3 |
| 2014486 | 6-Methylmercaptopurine | 32654-6 |
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
- 6 Methyl Mercaptopurine
- 6-Mercaptopurine
- 6-Methylmercaptopurine
- 6-MMP
- 6-MMPN
- 6-MP
- 6-TG
- 6-TGN
- 6-Thioguanine
- 6MMP
- 6MMPN
- 6MP
- 6TG
- 6TGN
- AZA
- FPMET
- Imuran Metabolite
- Mercaptopurine
- Methylmercaptopurine
- Purine antimetabolites
- Purinethol
- THIO
- Thioguanine
- Thiopurine
- Thiopurine Metabolites
- TPMT
- TPRBC
Thiopurine Metabolites by LC-MS/MS
Mayo Clinic Laboratories
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