Ordering Recommendation

Use to diagnose Gaucher disease only; not indicated for carrier screening.

Mnemonic
GBA ENZYME
Methodology

Quantitative Fluorometry

Performed

Varies

Reported

3-10 days

New York DOH Approval Status
This test is New York DOH approved.
Specimen Required
Patient Preparation
Collect

Yellow (ACD), Lavender (K2EDTA), Lavender (K3EDTA), or Green (Sodium Heparin).

Specimen Preparation

Transport 3 mL whole blood. (Min: 1 mL)

Storage/Transport Temperature

Refrigerated

Unacceptable Conditions

Grossly hemolyzed specimens.

Remarks

Additional information is required: Clinical Indication for testing.

Stability

Ambient: Unacceptable; Refrigerated: 3 days; Frozen: Unacceptable

Reference Interval

4.6 - 12.0 nmol hydrolyzed/hr/mg protein

Interpretive Data

Refer to report.

Compliance Statement B: For laboratory developed tests not using a RUO kit, and for FDA approved, cleared or 510(k) exempt assays with alterations. This test was developed and its performance characteristics determined by ARUP Laboratories. The U. S. Food and Drug Administration has not approved or cleared this test; however, FDA clearance or approval is not currently required for clinical use. The results are not intended to be used as the sole means for clinical diagnosis or patient management decisions.

Note
Hotline History
N/A
CPT Codes

82657

Components
Component Test Code* Component Chart Name LOINC
2014460 Gaucher GBA Activity Leukocytes Interp 48767-8
2014461 Gaucher GBA Activity Leukocytes 32540-7
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • Gaucher
  • GBA
  • glucocerebrosidase
  • glucosidase
Gaucher Disease (GBA), Enzyme Activity in Leukocytes