Allergens, Respiratory IgE Panel, Region 1, North Atlantic (CT, MA, NJ, PA, VT, ME, NH, NY, RI)

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Ordering Recommendation

Allergen testing for patients in the north Atlantic region (Connecticut, Massachusetts, New Jersey, Vermont, Maine, New Hampshire, and Rhode Island).

Mnemonic
REG1PAN
Methodology

Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Performed

Sun-Sat

Reported

1-2 days

New York DOH Approval Status
This test is New York DOH approved.
Specimen Required
Patient Preparation

Multiple patient encounters should be avoided.

Collect

Serum Separator Tube (SST). Multiple specimen tubes should be avoided.

Specimen Preparation

Separate from cells ASAP or within 2 hours of collection. Transfer 4 mL serum to an ARUP Standard Transport Tube. (Min: 1.4 mL)

Storage/Transport Temperature

Refrigerated.

Unacceptable Conditions

Hemolyzed, icteric, or lipemic specimens.

Remarks
Stability

After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year

Reference Interval
Allergens, Respiratory Panel, Region 1, North Atlantic (CT, MA, NJ, PA, VT, ME, NH, NY, RI)
Reference Intervals for all Components
Reporting Range
(reported in kU/L)
 Probability of IgE Mediated
Clinical Reaction
 Class Scoring
Less than 0.10 No significant level detected 0
0.10-0.34 Clinical relevance undetermined 0/1
0.35-0.70 Low 1
0.71-3.50 Moderate 2
3.51-17.50 High 3
17.51 - 50.00 Very High 4
50.01 - 100.00 Very High 5
Greater than 100.00 Very high 6

Test Number
 Components
 Reference Interval
0050345 Immunoglobulin E Effective November 17, 2014
Age
 Reference Interval
0-5 months 13 kU/L or less
6-12 months 34 kU/L or less
1-2 years 97 kU/L or less
3 years 199 kU/L or less
4-6 years 307 kU/L or less
7-8 years 403 kU/L or less
9-12 years 696 kU/L or less
13-15 years 629 kU/L or less
16-17 years 537 kU/L or less
18 years and older 214 kU/L or less

Interpretive Data

Allergen results of 0.10-0.34 kU/L are intended for specialist use as the clinical relevance is undetermined. Even though increasing ranges are reflective of increasing concentrations of allergen-specific IgE, these concentrations may not correlate with the degree of clinical response or skin testing results when challenged with a specific allergen. The correlation of allergy laboratory results with clinical history and in vivo reactivity to specific allergens is essential. A negative test may not rule out clinical allergy or even anaphylaxis.

Compliance Category

FDA

Note

Allergens included in this panel: Alternaria alternata (tenuis), Aspergillus fumigatus, Bermuda Grass, Birch Tree, Box Elder/Maple Tree, Cat Dander, Cockroach (German), Common Short Ragweed, Cottonwood Tree, D. pteronyssinus (mites), D. farinae (mites), Dog Dander, Elm Tree, Hormodendrum (Cladosporium), Mouse Epithelium, Mountain Cedar (Juniper) Tree, Mucor racemosus, Mugwort, Oak Tree, Penicillium notatum, Pigweed, Sheep Sorrel (Dock), Sycamore Tree, Timothy Grass, Walnut Tree, White Ash Tree, White Mulberry Tree, and IgE Serum Total.

Hotline History
N/A
CPT Codes

86003 x27; 82785

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Components
Component Test Code* Component Chart Name LOINC
0050345 Immunoglobulin E 19113-0
0055001 Allergen, Fungi/Mold, A. alternata IgE 6020-2
0055003 Allergen, Tree, Box Elder/Maple Tree IgE 7155-5
0055006 Allergen, Animal, Cat Dander IgE 6833-8
0055007 Allergen, Tree, Mountain Cedar Tree IgE 6178-8
0055010 Allergen, Tree, Cottonwood Tree IgE 6090-5
0055021 Allergen, Weed, Mugwort IgE 6183-8
0055025 Allergen, Weed, Pigweed IgE 7604-2
0055032 Allergen, Grass, Timothy Grass IgE 6265-3
0055038 Allergen, Fungi/Mold, Hormodendrum IgE 6075-6
0055042 Allergen, Tree, Elm Tree IgE 6109-3
0055045 Allergen, Tree, Oak Tree IgE 6189-5
0055058 Allergen, Tree, Birch Tree IgE 15283-5
0055061 Allergen, Fungi/Mold, A. fumigatus IgE 6025-1
0055063 Allergen, Mites, D. pteronyssinus IgE 6096-2
0055064 Allergen, Mites, D. farinae IgE 6095-4
0055070 Allergen, Grass, Bermuda Grass IgE 6041-8
0055073 Allergen, Tree, White Ash Tree IgE 6278-6
0055080 Allergen, Fungi/Mold, P. notatum IgE 6212-5
0055085 Allergen, Weed, Common/Short Ragweed IgE 6085-5
0055088 Allergen, Insect, Cockroach, German IgE 6078-0
0055090 Allergen, Tree, Sycamore Tree IgE 15285-0
0055093 Allergen, Tree, Walnut Tree IgE 33982-0
0055191 Allergen, Animal, Mouse Epithelium IgE 6179-6
0055442 Allergen, Fungi/Mold, M. racemosus IgE 6182-0
0099554 Allergen, Tree, White Mulberry Tree IgE 6281-0
0099568 Allergen, Animal, Dog Dander IgE 6098-8
0099785 Allergen, Weed, Sheep Sorrel IgE 6244-8
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
Allergens, Respiratory IgE Panel, Region 1, North Atlantic (CT, MA, NJ, PA, VT, ME, NH, NY, RI)