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Allergens, Respiratory IgE Panel, Region 1, North Atlantic (CT, MA, NJ, PA, VT, ME, NH, NY, RI)
Ordering Recommendation
Allergen testing for patients in the north Atlantic region (Connecticut, Massachusetts, New Jersey, Vermont, Maine, New Hampshire, and Rhode Island).
New York DOH Approval Status
Specimen Required
Multiple patient encounters should be avoided.
Serum Separator Tube (SST). Multiple specimen tubes should be avoided.
Separate from cells ASAP or within 2 hours of collection. Transfer 4 mL serum to an ARUP Standard Transport Tube. (Min: 1.4 mL)
Refrigerated.
Hemolyzed, icteric, or lipemic specimens.
After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year
Methodology
Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay
Performed
Sun-Sat
Reported
1-3 days
Reference Interval
| Test Number |
Components |
Reference Interval |
||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Immunoglobulin E |
|
|||||||||||||||||||||||
| Allergen, Fungi/Mold, A. alternata IgE | Less than or equal to 0.34 kU/L | |||||||||||||||||||||||
| Allergen, Tree, Box Elder/Maple Tree IgE | Less than or equal to 0.34 kU/L | |||||||||||||||||||||||
| Allergen, Animal, Cat Dander IgE | Less than or equal to 0.34 kU/L | |||||||||||||||||||||||
| Allergen, Tree, Mountain Cedar Tree IgE | Less than or equal to 0.34 kU/L | |||||||||||||||||||||||
| Allergen, Tree, Cottonwood Tree IgE | Less than or equal to 0.34 kU/L | |||||||||||||||||||||||
| Allergen, Weed, Mugwort IgE | Less than or equal to 0.34 kU/L | |||||||||||||||||||||||
| Allergen, Weed, Pigweed IgE | Less than or equal to 0.34 kU/L | |||||||||||||||||||||||
| Allergen, Grass, Timothy Grass IgE | Less than or equal to 0.34 kU/L | |||||||||||||||||||||||
| Allergen, Fungi/Mold, Hormodendrum IgE | Less than or equal to 0.34 kU/L | |||||||||||||||||||||||
| Allergen, Tree, Elm Tree IgE | Less than or equal to 0.34 kU/L | |||||||||||||||||||||||
| Allergen, Tree, Oak Tree IgE | Less than or equal to 0.34 kU/L | |||||||||||||||||||||||
| Allergen, Tree, Birch Tree IgE | Less than or equal to 0.34 kU/L | |||||||||||||||||||||||
| Allergen, Fungi/Mold, A. fumigatus IgE | Less than or equal to 0.34 kU/L | |||||||||||||||||||||||
| Allergen, Mites, D. pteronyssinus IgE | Less than or equal to 0.34 kU/L | |||||||||||||||||||||||
| Allergen, Mites, D. farinae IgE | Less than or equal to 0.34 kU/L | |||||||||||||||||||||||
| Allergen, Grass, Bermuda Grass IgE | Less than or equal to 0.34 kU/L | |||||||||||||||||||||||
| Allergen, Tree, White Ash Tree IgE | Less than or equal to 0.34 kU/L | |||||||||||||||||||||||
| Allergen, Fungi/Mold, P. notatum IgE | Less than or equal to 0.34 kU/L | |||||||||||||||||||||||
| Allergen, Weed, Common/Short Ragweed IgE | Less than or equal to 0.34 kU/L | |||||||||||||||||||||||
| Allergen, Insect, Cockroach, German IgE | Less than or equal to 0.34 kU/L | |||||||||||||||||||||||
| Allergen, Tree, Sycamore Tree IgE | Less than or equal to 0.34 kU/L | |||||||||||||||||||||||
| Allergen, Tree, Walnut Tree IgE | Less than or equal to 0.34 kU/L | |||||||||||||||||||||||
| Allergen, Animal, Mouse Epithelium IgE | Less than or equal to 0.34 kU/L | |||||||||||||||||||||||
| Allergen, Fungi/Mold, M. racemosus IgE | Less than or equal to 0.34 kU/L | |||||||||||||||||||||||
| Allergen, Tree, White Mulberry Tree IgE | Less than or equal to 0.34 kU/L | |||||||||||||||||||||||
| Allergen, Animal, Dog Dander IgE | Less than or equal to 0.34 kU/L | |||||||||||||||||||||||
| Allergen, Weed, Sheep Sorrel IgE | Less than or equal to 0.34 kU/L |
Interpretive Data
Allergen results of 0.10-0.34 kU/L are intended for specialist use as the clinical relevance is undetermined. Even though increasing ranges are reflective of increasing concentrations of allergen-specific IgE, these concentrations may not correlate with the degree of clinical response or skin testing results when challenged with a specific allergen. The correlation of allergy laboratory results with clinical history and in vivo reactivity to specific allergens is essential. A negative test may not rule out clinical allergy or even anaphylaxis.
| Reporting Range (reported in kU/L) |
Probability of IgE Mediated Clinical Reaction |
Class Scoring |
|---|---|---|
| Less than 0.10 | No significant level detected | 0 |
| 0.10 - 0.34 | Clinical relevance undetermined | 0/1 |
| 0.35 - 0.70 | Low | 1 |
| 0.71 - 3.50 | Moderate | 2 |
| 3.51 - 17.50 | High | 3 |
| 17.51 - 50.00 | Very high | 4 |
| 50.01 - 100.00 | Very high | 5 |
| Greater than 100.00 | Very high | 6 |
FDA
Note
Allergens included in this panel: Alternaria alternata (tenuis), Aspergillus fumigatus, Bermuda Grass, Birch Tree, Box Elder/Maple Tree, Cat Dander, Cockroach (German), Common Short Ragweed, Cottonwood Tree, D. pteronyssinus (mites), D. farinae (mites), Dog Dander, Elm Tree, Hormodendrum (Cladosporium), Mouse Epithelium, Mountain Cedar (Juniper) Tree, Mucor racemosus, Mugwort, Oak Tree, Penicillium notatum, Pigweed, Sheep Sorrel (Dock), Sycamore Tree, Timothy Grass, Walnut Tree, White Ash Tree, White Mulberry Tree, and IgE Serum Total.
Hotline History
CPT Codes
86003 x27; 82785
Components
| Component Test Code* | Component Chart Name | LOINC |
|---|---|---|
| 0050345 | Immunoglobulin E | 19113-0 |
| 0055001 | Allergen, Fungi/Mold, A. alternata IgE | 6020-2 |
| 0055003 | Allergen, Tree, Box Elder/Maple Tree IgE | 7155-5 |
| 0055006 | Allergen, Animal, Cat Dander IgE | 6833-8 |
| 0055007 | Allergen, Tree, Mountain Cedar Tree IgE | 6178-8 |
| 0055010 | Allergen, Tree, Cottonwood Tree IgE | 6090-5 |
| 0055021 | Allergen, Weed, Mugwort IgE | 6183-8 |
| 0055025 | Allergen, Weed, Pigweed IgE | 7604-2 |
| 0055032 | Allergen, Grass, Timothy Grass IgE | 6265-3 |
| 0055038 | Allergen, Fungi/Mold, Hormodendrum IgE | 6075-6 |
| 0055042 | Allergen, Tree, Elm Tree IgE | 6109-3 |
| 0055045 | Allergen, Tree, Oak Tree IgE | 6189-5 |
| 0055058 | Allergen, Tree, Birch Tree IgE | 15283-5 |
| 0055061 | Allergen, Fungi/Mold, A. fumigatus IgE | 6025-1 |
| 0055063 | Allergen, Mites, D. pteronyssinus IgE | 6096-2 |
| 0055064 | Allergen, Mites, D. farinae IgE | 6095-4 |
| 0055070 | Allergen, Grass, Bermuda Grass IgE | 6041-8 |
| 0055073 | Allergen, Tree, White Ash Tree IgE | 6278-6 |
| 0055080 | Allergen, Fungi/Mold, P. notatum IgE | 6212-5 |
| 0055085 | Allergen, Weed, Common/Short Ragweed IgE | 6085-5 |
| 0055088 | Allergen, Insect, Cockroach, German IgE | 6078-0 |
| 0055090 | Allergen, Tree, Sycamore Tree IgE | 15285-0 |
| 0055093 | Allergen, Tree, Walnut Tree IgE | 33982-0 |
| 0055191 | Allergen, Animal, Mouse Epithelium IgE | 6179-6 |
| 0055442 | Allergen, Fungi/Mold, M. racemosus IgE | 6182-0 |
| 0099554 | Allergen, Tree, White Mulberry Tree IgE | 6281-0 |
| 0099568 | Allergen, Animal, Dog Dander IgE | 6098-8 |
| 0099785 | Allergen, Weed, Sheep Sorrel IgE | 6244-8 |
