Ordering Recommendation

Detect neutralizing antibodies to coxsackie A9 virus, coxsackie B virus, echovirus (types 6, 7, 9, 11, and 30), and poliovirus (types 1 and 3). Individual component tests are available (0050503, 0060055, 0060053 and 2014107).

Mnemonic

ENT AB PAN

Methodology

Serum Neutralization/Complement Fixation

Performed

Mon-Fri

Reported

6-12 days

New York DOH Approval Status

This test is New York DOH approved.

Specimen Required

Patient Preparation
Collect

Serum Separator Tube (SST).

Specimen Preparation

Separate from cells ASAP or within 2 hours of collection. Transfer 2 mL serum to an ARUP Standard Transport Tube. (Min: 0.75 mL) Parallel testing is preferred and convalescent specimens must be received within 30 days from receipt of the acute specimens. Mark specimens plainly as "acute" or "convalescent."

Storage/Transport Temperature

Refrigerated.

Unacceptable Conditions

Contaminated, hemolyzed, or severely lipemic specimens.

Remarks
Stability

After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles)

Reference Interval

Test Number
Components
Reference Interval
  Coxsackie A Serotype 9 Titer < 1:8
  Coxsackie B Virus Antibody Type 1 Less than 1:10
  Coxsackie B Virus Antibody Type 2 Less than 1:10
  Coxsackie B Virus Antibody Type 3 Less than 1:10
  Coxsackie B Virus Antibody Type 4 Less than 1:10
  Coxsackie B Virus Antibody Type 5 Less than 1:10
  Coxsackie B Virus Antibody Type 6 Less than 1:10
  Echovirus Antibody Type 6 Less than 1:10
  Echovirus Antibody Type 7 Less than 1:10
  Echovirus Antibody Type 9 Less than 1:10
  Echovirus Antibody Type 11 Less than 1:10
  Echovirus Antibody Type 30 Less than 1:10

Interpretive Data

Refer to report.


Component Interpretation
Poliovirus (Types 1, 3) Antibodies Less than 1:10  No detectable poliovirus antibodies.
1:10 or greater  Antibody to poliovirus detected, which may represent prior immunization or current or past infection.

Compliance Category

Standard

Note

Hotline History

N/A

CPT Codes

86658 x14

Components

Component Test Code* Component Chart Name LOINC
0050503 Coxsackie A Serotype 9 Titer 9757-6
0065111 Coxsackie B Virus Antibody Type 1 5103-7
0065112 Coxsackie B Virus Antibody Type 2 5105-2
0065113 Coxsackie B Virus Antibody Type 3 5107-8
0065114 Echovirus Antibody Type 6 5144-1
0065116 Echovirus Antibody Type 7 41492-0
0065117 Echovirus Antibody Type 11 41489-6
0065119 Echovirus Antibody Type 30 41491-2
0065123 Coxsackie B Virus Antibody Type 5 5111-0
0065124 Coxsackie B Virus Antibody Type 6 5113-6
0065126 Polio Virus Antibody Type 1 5281-1
0065128 Polio Virus Antibody Type 3 5285-2
0065130 Coxsackie B Virus Antibody Type 4 5109-4
0065132 Echovirus Antibody Type 9 5146-6
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.

Aliases

  • Coxsackie A
  • Coxsackie B
  • Echovirus
  • Ent Pan
  • Enterovirus Antibodies Profile
  • Enterovirus Panel
  • non-polio enterovirus testing
Enterovirus Antibodies Panel