Ordering Recommendation

Detect neutralizing antibodies to poliovirus (types 1 and 3).

Mnemonic
POLIO AB
Methodology

Semi-Quantitative Serum Neutralization

Performed

Mon-Fri

Reported

6-9 days

New York DOH Approval Status
This test is New York DOH approved.
Specimen Required
Patient Preparation
Collect

Serum Separator Tube (SST) or Plain Red.

Specimen Preparation

Separate from cells ASAP or within 2 hours of collection. Transfer 1 mL serum to an ARUP Standard Transport Tube. (Min: 0.2 mL)

Storage/Transport Temperature

Refrigerated.

Unacceptable Conditions

Plasma. Contaminated, hemolyzed, or severely lipemic specimens.

Remarks
Stability

After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles)

Reference Interval
Less than 1:10 No detectable poliovirus antibodies.
1:10 or greater Antibody to poliovirus detected, which may represent prior immunization or current or past infection.

Interpretive Data

The presence of neutralizing antibodies against poliovirus implies immunity. The serum neutralization test is serotype specific. Antibodies against one type does not indicate immunity against the other type.

Reference interval applies to Poliovirus Antibodies Types 1 and 3.

Compliance Category

Standard

Note
Hotline History
N/A
CPT Codes

86658 x2

Components
Component Test Code* Component Chart Name LOINC
0065126 Polio Virus Antibody Type 1 5281-1
0065128 Polio Virus Antibody Type 3 5285-2
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • Enterovirus; Poliovirus (1,3) Abs
  • Poliovirus (Types 1,3) Abs
  • Poliovirus (Types 1,3) Antibodies
  • Poliovirus 1, 3 Antibody (Immune Status)
  • Poliovirus Antibodies
  • Poliovirus Antibody, Neutralization
Poliovirus (Types 1, 3) Antibodies