Testing should only be performed on individuals meeting Centers for Disease Control and Prevention (CDC) clinical criteria for Zika virus (eg, clinical signs and symptoms associated with Zika virus infection) and/or CDC epidemiological criteria for Zika virus (eg, history of residence in or travel to a geographic region with active Zika transmission at the time of travel, or other epidemiological criteria for which Zika virus testing may be indicated).
Qualitative Polymerase Chain Reaction
Mon, Wed, Fri
Urine and patient-matched Serum Separator Tube (SST).
Urine: Transfer 1 mL urine to a sterile container. (Min: 0.5 mL)
Serum: Collect and retain 2 mL of patient-matched serum at the client site in the event that serological follow-up testing is needed. (Min: 1 mL)
Serum (refer to Zika Virus by PCR, Blood, ARUP test code 2014065).
Specimen source required.
Ambient: Unacceptable; Refrigerated: 5 days; Frozen: 6 weeks
Zika Virus by PCR is a real-time RT-PCR test intended for the qualitative detection of Zika virus RNA from individuals meeting CDC Zika virus clinical criteria (e.g., clinical signs and symptoms associated with Zika virus infection) and/or CDC Zika virus epidemiological criteria (e.g., history of residence in or travel to a geographic region with active Zika transmission at the time of travel, or other epidemiologic criteria for which Zika virus testing may be indicated).
Health care providers are strongly encouraged to collect serum specimens alongside other specimen types to provide additional opportunities for diagnosing Zika. A positive RT-PCR result confirms Zika virus infection, and no additional testing is indicated. When test results are negative for urine, the patient-matched serum should be tested as outlined in the current CDC-issued algorithm (https://www.cdc.gov/zika/laboratories/lab-guidance.html).
If serologic testing is needed on a patient-matched serum specimen, contact ARUP client services to order Zika Virus IgM Antibody Capture (MAC), by ELISA (ARUP test code 2013942). Additional charges apply.
The Zika Virus by PCR test is for in vitro diagnostic use under the FDA Emergency Use Authorization (EUA). This test has not been FDA cleared or approved. In compliance with this authorization, please visit https://aruplab.com/zika for more information and to access the applicable information sheets.
Emergency Use Authorization (EUA)
|Component Test Code*||Component Chart Name||LOINC|
|2014070||Zika Virus, Urine, Source||31208-2|
|2014071||Zika Virus by PCR, Urine||79190-5|