Ordering Recommendation

Specific indicator of pancreatic damage. Patients with acute pancreatitis have significantly elevated concentrations.

Mnemonic
TRYPS
Methodology

Quantitative Radioimmunoassay

Performed

Tue, Fri

Reported

1-5 days

New York DOH Approval Status
This test is New York DOH approved.
Specimen Required
Patient Preparation
Collect

Serum Separator Tube (SST) or Plain Red.

Specimen Preparation

Allow specimen to clot for 15-20 minutes at room temperature  Separate from cells ASAP or within 2 hours of collection.  Transfer 1 mL serum to an ARUP Standard Transport Tube. (Min: 0.3 mL)

Storage/Transport Temperature

Frozen

Unacceptable Conditions

Plasma or cord blood.  Grossly hemolyzed or lipemic specimens.

Remarks
Stability

After separation from cells:  Ambient: 2 hours; Refrigerated: 24 hours; Frozen: 3 months

Reference Interval
Age Reference Interval
0-17 years Not established
18 years and older 180.5-885.3 ng/mL

Interpretive Data

Results should be correlated with clinical presentation and other diagnostic data for the diagnosis of pancreatitis. Individuals with acute pancreatitis have significantly elevated trypsin concentrations. Concentrations in those with chronic pancreatitis are variable and may be below, within, or above the reference interval. Trypsin concentrations are not diagnostic for carcinoma of the pancreas. Results obtained with different assay methods or kits cannot be used interchangeably.

Compliance Category

FDA

Note
Hotline History
N/A
CPT Codes

83519

Components
Component Test Code* Component Chart Name LOINC
2014026 Trypsin 33325-2
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
Trypsin