Polymyositis Panel
Ordering Recommendation
May be useful for evaluation of patients with progressive proximal muscle weakness and antisynthetase syndrome.
New York DOH Approval Status
Specimen Required
Serum Separator Tube (SST).
Separate from cells ASAP or within 2 hours of collection. Transfer two 1 mL serum aliquots to ARUP Standard Transport Tubes. (Min: 0.5 mL/aliquot)
Refrigerated.
Hemolyzed, hyperlipemic, icteric, heat-treated or contaminated specimens.
Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 month
Methodology
Qualitative Immunoprecipitation/Semi-Quantitative Multiplex Bead Assay
Performed
Mon, Tue, Thu, Fri
Reported
7-18 days
Reference Interval
Test Number |
Components |
Reference Interval |
---|---|---|
Jo-1 (Histidyl-tRNA Synthetase) Ab, IgG | 40 AU/mL or less | |
PL-7 (threonyl-tRNA synthetase) Antibody | Negative | |
PL-12 (alanyl-tRNA synthetase) Antibody | Negative | |
EJ (glycyl-tRNA synthetase) Antibody | Negative | |
SRP (Signal Recognition Particle) Ab | Negative | |
OJ (isoleucyl-tRNA synthetase) Antibody | Negative |
Interpretive Data
Refer to report.
This test was developed and its performance characteristics determined by ARUP Laboratories. It has not been cleared or approved by the US Food and Drug Administration. This test was performed in a CLIA certified laboratory and is intended for clinical purposes.
Component | Interpretation | |
---|---|---|
Jo-1 Antibody, IgG | 29 AU/mL or less 30-40 AU/mL 41 AU/mL or greater |
Negative Equivocal Positive |
Laboratory Developed Test (LDT)
Note
Antibodies: PL-7, PL12, EJ, OJ, SRP, Jo-1
Hotline History
CPT Codes
83516 x5; 86235
Components
Component Test Code* | Component Chart Name | LOINC |
---|---|---|
0099592 | Jo-1 (Histidyl-tRNA Synthetase) Ab, IgG | 33571-1 |
2010853 | PL-7 (threonyl-tRNA synthetase) Antibody | 33772-5 |
2010854 | PL-12 (alanyl-tRNA synthetase) Antibody | 33771-7 |
2010856 | EJ (glycyl-tRNA synthetase) Antibody | 45149-2 |
2010859 | SRP (Signal Recognition Particle) Ab | 33921-8 |
2010860 | OJ (isoleucyl-tRNA synthetase) Antibody | 45152-6 |
2013995 | Polymyositis Interpretive Information | 48767-8 |