Polymyositis Panel

2013990
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Negative
Positive

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Additional Technical Information

Ordering Recommendation

May be useful for evaluation of patients with progressive proximal muscle weakness and antisynthetase syndrome.

Mnemonic

POLY MYO

Methodology

Qualitative Immunoprecipitation/Semi-Quantitative Multiplex Bead Assay

Performed

Mon, Tue, Thu, Fri

Reported

7-18 days

New York DOH Approval Status

This test is New York DOH approved.

Specimen Required

Patient Preparation
Collect

Serum Separator Tube (SST).

Specimen Preparation

Separate from cells ASAP or within 2 hours of collection. Transfer two 1 mL serum aliquots to ARUP Standard Transport Tubes. (Min: 0.5 mL/aliquot)

Storage/Transport Temperature

Refrigerated.

Unacceptable Conditions

Hemolyzed, hyperlipemic, icteric, heat-treated or contaminated specimens.

Remarks
Stability

Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 month

Reference Interval

Test Number
 Components
 Reference Interval
  Jo-1 (Histidyl-tRNA Synthetase) Ab, IgG 40 AU/mL or less
  PL-7 (threonyl-tRNA synthetase) Antibody Negative
  PL-12 (alanyl-tRNA synthetase) Antibody Negative
  EJ (glycyl-tRNA synthetase) Antibody Negative
  SRP (Signal Recognition Particle) Ab Negative
  OJ (isoleucyl-tRNA synthetase) Antibody Negative

Interpretive Data

Refer to report.

This test was developed and its performance characteristics determined by ARUP Laboratories. It has not been cleared or approved by the US Food and Drug Administration. This test was performed in a CLIA certified laboratory and is intended for clinical purposes.


Component Interpretation
Jo-1 Antibody, IgG 29 AU/mL or less
30-40 AU/mL
41 AU/mL or greater		 Negative
Equivocal
Positive

Compliance Category

Laboratory Developed Test (LDT)

Note

Antibodies: PL-7, PL12, EJ, OJ, SRP, Jo-1

Hotline History

View Hotline History

 

Hotline History

Date of Change
Test Name Change
Methodology
Performance/Reported Schedule
Specimen Requirements
Reference Interval
Interpretive Data
Note
CPT Code
Component Change
Other Interface Change
New Test
Inactive
02/22/2022
X
N/A

CPT Codes

83516 x5; 86235

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Components

Component Test Code* Component Chart Name LOINC
0099592 Jo-1 (Histidyl-tRNA Synthetase) Ab, IgG 33571-1
2010853 PL-7 (threonyl-tRNA synthetase) Antibody 33772-5
2010854 PL-12 (alanyl-tRNA synthetase) Antibody 33771-7
2010856 EJ (glycyl-tRNA synthetase) Antibody 45149-2
2010859 SRP (Signal Recognition Particle) Ab 33921-8
2010860 OJ (isoleucyl-tRNA synthetase) Antibody 45152-6
2013995 Polymyositis Interpretive Information 48767-8
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.

Aliases

Polymyositis Panel