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Epi proColon
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The Epi proColon test is indicated to screen adults of either sex, 50 years or older, defined as average risk for CRC, who have been offered and have a history of not completing CRC screening. Tests that are available and recommended in the USPSTF 2008 CRC screening guidelines should be offered and declined prior to offering the Epi proColon test. Patients with a positive Epi proColon test result should be referred for diagnostic colonoscopy. The Epi proColon test results should be used in combination with physician's assessment and individual risk factors in guiding patient management.
Polymerase Chain Reaction
Sun, Wed
7-10 days
Lavender (K2EDTA). Collect 20 mL whole blood. (Min: 10 mL). Blood collection tubes should be allowed to complete the evacuated fill.
Plasma preparation should be performed ASAP or within 4 hours of collection. Centrifuge for 12 min at 1350 ± 150 rcf. Transfer the plasma to a 15 mL conical tube and centrifuge for an additional 12 minutes at 1350 ± 150 rcf. Ensure a minimum of 8 mL plasma is obtained following centrifugation. Transfer 4 mL plasma into 2 cryovial tubes or freezable specimen transport tubes. (Min: 4 mL, no repeat testing)
Frozen. Also acceptable: Refrigerated.
Serum, stool, or whole blood. Hemolyzed specimens.
Ambient: Unacceptable; Refrigerated: 72 hours; Frozen: 2 weeks
Refer to report.
No compliance statements are in use for this test.
This test is not intended to replace a colonoscopy. NOT recommended for pregnant women because of a potential for false-positive results in these individuals.
Accurate test performance requires following the specimen preparation instructions. Minimum volume of 4 mL is required for testing without repeats. If a repeat is necessary, an additional specimen will be requested.
81327
| Component Test Code* | Component Chart Name | LOINC |
|---|---|---|
| 2013907 | Epi proColon Result | 65810-4 |
- ColoVantage
- mS9
- Septin 9
- Septin 9 methylation
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