Ordering Recommendation

Use in appropriate high-risk patients (eg, type 2 diabetes mellitus) in whom LDL particle number is being used to guide therapy. Not recommended for cardiovascular disease risk assessment in most individuals; preferred test is Lipid Panel (0020421).

New York DOH Approval Status

This test is New York state approved.

Specimen Required

Patient Preparation

Fast 12 hours prior to collection.


Greiner Bio-One Clot Activator Tube (ARUP supply #54325) available online through eSupply using ARUP Connect ™ or by contacting ARUP Client Services at (800) 522-2787. Also acceptable: Plain Red.

Specimen Preparation

Gently invert tube to mix contents; allow to clot at room temperature. Separate from cells within 8 hours. Transfer 4 mL serum to an ARUP Standard Transport Tube with "ARUP NMR Serum" label (ARUP supply #55652). Labels are available online through eSupply using ARUP Connect ™ or by contacting ARUP Client Services at (800) 522-2787. (Min: 2 mL)

Storage/Transport Temperature


Unacceptable Conditions

Plasma. Serum separator tubes other than Greiner Bio-One. Non-fasting or lipemic specimens.


Ambient: 24 hours; Refrigerated: 2 weeks; Frozen: Unacceptable


Quantitative Nuclear Magnetic Resonance Spectroscopy/ Quantitative Enzymatic Assay/Detergent Solubilization




3-6 days

Reference Interval

By report

Interpretive Data

This test was developed and its performance characteristics determined by ARUP Laboratories. It has not been cleared or approved by the US Food and Drug Administration. This test was performed in a CLIA certified laboratory and is intended for clinical purposes.

Compliance Category

Laboratory Developed Test (LDT)


Refer to the Test Mix Addendum for interface build information.

Hotline History


CPT Codes

83704; 80061


Component Test Code* Component Chart Name LOINC
2001895 Total Cholesterol 2093-3
2001899 Triglycerides 2571-8
2001900 HDL Cholesterol 2085-9
2001901 LDL Cholesterol, Calc 13457-7
2013717 HDL Particle Size, NMR 62253-0
2013718 VLDL Particle Size, NMR 62254-8
2013719 LDL Particle Size, NMR 17782-4
2013720 Large HDL Particle Number, NMR 43729-3
2013721 HDL Particle Number, NMR 49748-7
2013722 Large VLDL Particle Number, NMR 43728-5
2013723 Small LDL Particle Number, NMR 43727-7
2013724 LDL Particle Number, NMR 54434-6
2013762 EER LipoFit by NMR 11526-1
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.


  • Cholesterol (NMR LipoProfile Test)
  • Expanded (NMR LipoProfile Test)
  • FNMR (NMR LipoProfile Test)
  • HDL Particle
  • LDL Particle
  • Lipid Particle Concentration
  • Lipid Particle Size
  • Lipid Profile, NMR
  • LipoMed (NMR LipoProfile Test)
  • Lipoprotein Analysis (LDL-P, HDL-P, VLDL-P, LDL Size, HDL Size, VLDL Size)
  • Lipoprotein Particle
  • VLDL Particle
LipoFit by NMR