Ordering Recommendation

May be useful in clinical research settings to evaluate progression of certain cancers.

Mnemonic
P53 MUTAT
Methodology

Polymerase Chain Reaction/Sequencing

Performed

Varies

Reported

3-11 days

New York DOH Approval Status
This test is New York DOH approved.
Specimen Required
Patient Preparation
Collect

Lavender (EDTA) or Pink (K2EDTA). Also acceptable: Paraffin embedded tissue.

Specimen Preparation

Transport 6 mL whole blood (Min: 3 mL) OR 3 mL bone marrow (Min: 1 mL). Transport tissue block in a tissue transport kit (ARUP supply #47808) available online through eSupply using ARUP Connect ™ or contact ARUP Client Services at (800) 522-2787.
Test is not performed at ARUP; separate specimens must be submitted when multiple tests are ordered.

Storage/Transport Temperature

Refrigerated. Also acceptable: Room temperature.

Unacceptable Conditions
Remarks
Stability

Whole Blood or Bone Marrow: Ambient: 72 hours; Refrigerated: 1 week; Frozen: Unacceptable
Paraffin Embedded Tissue: Ambient: Indefinitely; Refrigerated: Indefinitely; Frozen: Unacceptable

Reference Interval
Interpretive Data



Compliance Category

Performed by non-ARUP Laboratory

Note
Hotline History
N/A
CPT Codes

81405

Components
Component Test Code* Component Chart Name LOINC
2013485 TP53 Somatic Mutation, Prognostic
2013486 TP53 Exon 4 Mutation
2013487 TP53 Exon 5 Mutation
2013488 TP53 Exon 6 Mutation
2013489 TP53 Exon 7 Mutation
2013490 TP53 Exon 8 Mutation
2013491 TP53 Exon 9 Mutation
2013492 TP53 Somatic Mutation, Interpretation
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
TP53 Somatic Mutation, Prognostic

Quest Diagnostics San Juan Capistrano Inc.