Time Sensitive

Ordering Recommendation

New York DOH Approval Status

This test is New York state approved.

Specimen Required

Patient Preparation

Muscle biopsy.

Specimen Preparation

Obtain Muscle/Nerve Biopsy collection kit prior to collection procedure, (ARUP supply #40923) available online through eSupply using ARUP Connect™ or contact Client Services at (800)522-2787. Special fixatives are required; collection instructions are provided with the kit. 

Storage/Transport Temperature

Room temperature. Also acceptable: Refrigerated. Ship in cooled container during summer months.

Unacceptable Conditions

Specimens submitted with non-representative tissue type. Specimens that are not collected according to the collection instructions provided in the collection kit.


Submit electronic request. If you do not have electronic ordering capability, use an ARUP Anatomic Pathology Form (#32960) with an ARUP client number. For additional technical details, contact ARUP Client Services at (800) 522-2787. Submit clinical history.


Ambient: 24 hours; Refrigerated: 24 hours; Frozen: Unacceptable


Microscopy/Immunohistochemistry/Immunofluorescence/Electron Microscopy




1-7 days

Reference Interval

Interpretive Data

Refer to report.

Compliance Category

Varies by Report


Detailed collection instructions are available in the Muscle Biopsy Collection Kit (#40923) or can be requested by contacting ARUP Client Services at (800) 522-2787. Use of a different collection kit could result in sub-optimal biopsy preparation or fixation and delays in diagnosis. All vials must be labeled with the patient's full name and unique identifier. Avoid drying of specimens; make sure the fresh specimens are completely moist with saline gauze and fixed specimen are submerged into the fixative and not caught on vial sides or in the threads of the cap. Please acquire and use ARUPs Muscle Biopsy Collection Kit as the instructions and contents make the muscle collection procedure safer and easier.

Testing is ordered at the discretion of the ARUP pathologist; charges vary by individual patient.

Hotline History


CPT Codes

CPT codes vary by individual patient


Component Test Code* Component Chart Name LOINC
8070000 Submitting Physician 18781-5
8070010 Clinical History 22636-5
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.


  • consultation
  • muscle
  • nerve
Comprehensive Muscle Biopsy Workup