Ordering Recommendation

Detect and quantify herpesvirus 8 (HHV-8).




Quantitative Polymerase Chain Reaction


Mon, Thu


2-5 days

New York DOH Approval Status

This test is New York DOH approved.

Specimen Required

Patient Preparation

Lavender (EDTA), Pink (K2 EDTA), or Serum Separator Tube (SST).

Specimen Preparation

Separate serum or plasma from cells. Transport 1 mL plasma, serum, or whole blood in a sterile container. (Min: 0.5 mL)

Storage/Transport Temperature


Unacceptable Conditions

Heparinized specimens, tissues in optimal cutting temperature compound.


Specimen source required.


Ambient: 24 hours; Refrigerated: 1 week; Frozen: 1 year

Reference Interval

Not detected

Interpretive Data

The quantitative range of this assay is 3.8-8.8 log copies/mL (6,670 - 667,000,000 copies/mL).

A negative result (less than 3.8 log copies/mL or less than 6,670 copies/mL) does not rule out the presence of PCR inhibitors in the patient specimen or HHV8 DNA concentrations below the level of detection of the test. Inhibition may also lead to underestimation of viral quantitation.

No international standard is currently available for calibration of this assay. Caution should be taken when interpreting results generated by different assay methodologies.

This test was developed and its performance characteristics determined by ARUP Laboratories. It has not been cleared or approved by the US Food and Drug Administration. This test was performed in a CLIA certified laboratory and is intended for clinical purposes.

Compliance Category

Laboratory Developed Test (LDT)


The limit of quantification for this DNA test is 3.8 log copies/mL (6,670 copies/mL). If the test DID NOT DETECT the virus, the test result will be reported as "< 3.8 log copies/mL (< 6,670 copies/mL)." If the test DETECTED the presence of the virus but was not able to accurately quantify the number of copies, the test result will be reported as "Not Quantified."

Hotline History


CPT Codes



Component Test Code* Component Chart Name LOINC
2013090 HHV8 by Quantitative PCR, Source 31208-2
2013091 HHV8 by Quantitative PCR, Copy/mL 49404-7
2013092 HHV8 by Quantitative PCR, Log copy/mL
2013093 HHV8 by Quantitative PCR, Interp 39083-1
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.


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Human Herpesvirus 8 (HHV-8) by Quantitative PCR