Ordering Recommendation

Acceptable panel for second-line testing for antiphospholipid syndrome (APS) risk estimation when results for aPL criteria tests are negative or equivocal.

Mnemonic

NCAPS PAN

Methodology

Semi-Quantitative Enzyme-Linked Immunosorbent Assay

Performed

Thu

Reported

1-8 days

New York DOH Approval Status

This test is New York DOH approved.

Specimen Required

Patient Preparation
Collect

Serum separator tube (SST).

Specimen Preparation

Separate serum from cells ASAP or within 2 hours of collection. Transfer 1.5 mL serum to an ARUP Standard Transport Tube. (Min: 0.9 mL)

Storage/Transport Temperature

Refrigerated.

Unacceptable Conditions

Heat-inactivated, grossly hemolyzed, icteric, or lipemic specimens.

Remarks
Stability

After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 month

Reference Interval

Test Number
Components
Reference Interval
  Phosphatidylserine Antibody IgG Less than 16 GPS
  Phosphatidylserine Antibody IgM Less than  22 MPS
  Prothrombin Antibody, IgG Less than 20 Units
  Phosphatidylserine and Prothrombin IgG 0-30 Units
  Phosphatidylserine and Prothrombin IgM 0-30 Units

Interpretive Data

Refer to report.

Compliance Category

FDA

Note

Hotline History

N/A

CPT Codes

86148 x2; 83516 x2; 86849

Components

Component Test Code* Component Chart Name LOINC
0050906 Phosphatidylserine Antibody IgG 32032-5
0050907 Phosphatidylserine Antibody IgM 32033-3
0051302 Prothrombin Antibody, IgG 40595-1
2009448 Phosphatidylserine and Prothrombin IgG 85359-8
2009450 Phosphatidylserine and Prothrombin IgM 85358-0
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.

Aliases

  • ACA and non-criteria APS panel
  • aCL and non-criteria APS panel
  • aCL and non-criteria APS;
  • APS aCL and non-criteria panel
Non-Criteria Antiphospholipid Syndrome (APS) (aPs, aPt, aPs/aPt) Antibodies Panel