Ordering Recommendation

Screen, diagnose, and monitor diseases associated with excess or deficient cortisol production.

Mnemonic

FCORTS TMS

Methodology

Equilibrium Dialysis/Quantitative High Performance Liquid Chromatography-Tandem Mass Spectrometry

Performed

Sun, Tue, Thu, Fri

Reported

2-5 days

New York DOH Approval Status

This test is New York DOH approved.

Specimen Required

Patient Preparation

Recommended collection times are 8-10 a.m. or 4-6 p.m. 

Collect

Plain red or serum separator tube, lavender (EDTA) or pink (K2EDTA).

Specimen Preparation

Separate serum or plasma from cells within 2 hours of collection. Transfer 1 mL serum or plasma to an ARUP Standard Transport Tube. (Min: 0.6 mL)

Storage/Transport Temperature

Frozen.

Unacceptable Conditions

Grossly hemolyzed, icteric, lipemic or heparinized specimens. 

Remarks

Indicate time of draw on test request form and specimen tube.

Stability

After separation from cells: Ambient: Unacceptable; Refrigerated: 1 week; Frozen: 6 months

Reference Interval

Age Time of Collection Reference Range
0 - 17 years Not established
18 years of age and older 8-10 a.m. collection 0.21 - 1.04 µg/dL
18 years of age and older 4-6 p.m. collection 0.10 - 0.63 µg/dL

Interpretive Data

This test was developed and its performance characteristics determined by ARUP Laboratories. It has not been cleared or approved by the US Food and Drug Administration. This test was performed in a CLIA certified laboratory and is intended for clinical purposes.

Compliance Category

Laboratory Developed Test (LDT)

Note

To convert to nmol/L, multiply µg/dL by 27.6.

Hotline History

N/A

CPT Codes

82530

Components

Component Test Code* Component Chart Name LOINC
2012698 Cortisol, Free by ED/LC-MS/MS 2145-1
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.

Aliases

  • Hydrocortisone, Free
Cortisol, Free by Equilibrium Dialysis/LC-MS/MS