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HLA-DRB1 by Next Generation Sequencing
2012494
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Ordering Recommendation
The intended use of this test is pre-transplant allele matching. Do not use for HLA-related disease screening or diagnosis (eg, celiac disease, narcolepsy, rheumatologic diseases).
Mnemonic
HLA DRB1
Methodology
Polymerase Chain Reaction/Massively Parallel Sequencing
Performed
Varies
Reported
10-13 days
New York DOH Approval Status
Specimens from New York clients will be sent out to a New York DOH approved laboratory, if possible.
Specimen Required
Patient Preparation
Collect
Lavender (EDTA). Also acceptable: yellow (ACD Solution A).
Specimen Preparation
Transport 4 mL whole blood in original container. (Min: 1 mL)
Storage/Transport Temperature
Refrigerated.
Unacceptable Conditions
Yellow (ACD Solution B) specimens. Clotted, grossly hemolyzed, or heparinized specimens.
Remarks
Stability
Ambient: 72 hours; Refrigerated: 1 week; Frozen: Unacceptable
Reference Interval
By Report
Interpretive Data
No compliance statements are in use for this test.
Note
Hotline History
N/A
CPT Codes
81382
Components
| Component Test Code* | Component Chart Name | LOINC |
|---|---|---|
| 2012495 | HLA-DRB1*, Class II - Locus, Allele 1 | |
| 2012496 | HLA-DRB1*, Class II - Locus, Allele 2 | |
| 2012497 | HLA-DRB1 by NGS, Interpretation |
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
HLA-DRB1 by Next Generation Sequencing
Children’s Hospital of Philadelphia
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