Ordering Recommendation
Mnemonic
MILK COMP
Methodology

Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Performed

Sun-Sat

Reported

1-2 days

New York DOH Approval Status
This test is New York DOH approved.
Specimen Required
Patient Preparation

Multiple patient encounters should be avoided.

Collect

Serum separator tube. Multiple specimen tubes should be avoided.

Specimen Preparation

Separate serum from cells ASAP or within 2 hours of collection. Transfer 1 mL serum plus 0.1 mL for each additional allergen ordered to an ARUP Standard Transport Tube. (Min: 0.5 mL plus 0.04 mL for each allergen ordered)

Storage/Transport Temperature

Refrigerated.

Unacceptable Conditions

Hemolyzed, icteric, or lipemic specimens.

Remarks
Stability

After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year

Reference Interval
Reporting Range
(reported in kU/L)
Probability of IgE Mediated
Clinical Reaction
Class Scoring
Less than 0.10 No significant level detected 0
0.10 - 0.34 Clinical relevance undetermined 0/1
0.35 - 0.70 Low 1
0.71 - 3.50 Moderate 2
3.51 - 17.50 High 3
17.51 - 50.00 Very high 4
50.01 - 100.00 Very high 5
Greater than 100.00 Very high 6

Interpretive Data

Allergen results of 0.10-0.34 kU/L are intended for specialist use as the clinical relevance is undetermined. Even though increasing ranges are reflective of increasing concentrations of allergen-specific IgE, these concentrations may not correlate with the degree of clinical response or skin testing results when challenged with a specific allergen. The correlation of allergy laboratory results with clinical history and in vivo reactivity to specific allergens is essential. A negative test may not rule out clinical allergy or even anaphylaxis. 

Alpha-lactoalbumin (Bos d 4) and Beta-lactoglobulin (Bos d 5) are heat labile and associated with a risk for reaction to fresh milk. Casein (Bos d 8) is heat stable and associated with a risk for reaction to all forms of milk. Note:  Allergens included in this panel:  Alpha-lactoalbumin (Bos d 4), Beta-lactoglobulin (Bos d 5), Casein (Bos d 8) and Milk (Cows).

No compliance statements are in use for this test.

Note
Hotline History
N/A
CPT Codes

86003; 86008 x3

Components
Component Test Code* Component Chart Name LOINC
0055020 Allergen, Food, Milk (Cow) IgE 7258-7
0055074 Allergen, Food, Beta-lactoglobulin IgE 41397-1
0055081 Allergen, Food, Casein IgE 6062-4
0099543 Allergen, Food, Alpha-Lactalbumin IgE 7445-0
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • ImmunoCap (f76, f77, f78, f2) Milk Allergen Components
  • Milk Component Panel
  • Milk Components
Allergen, Food, Milk (Cows) Components IgE