Determine etiology of unexplained hemolytic anemia or family history of unexplained hemolytic anemia and in neonates with unexplained hyperbilirubinemia.
Massively Parallel Sequencing
Lavender (EDTA) or yellow (ACD Solution A or B).
Transport 3 mL whole blood. (Min: 1 mL)
Ambient: 72 hours; Refrigerated: 1 week; Frozen: Unacceptable
Refer to report.
Compliance Statement C: For human genetic inheritable conditions and mutations. This test was developed and its performance characteristics determined by ARUP Laboratories. The U. S. Food and Drug Administration has not approved or cleared this test; however, FDA clearance or approval is not currently required for clinical use. The results are not intended to be used as the sole means for clinical diagnosis or patient management decisions.
Counseling and informed consent are recommended for genetic testing. Consent forms are available online.
Recent CBC result is required.
GENES TESTED: AK1, ALDOA, ANK1, CDAN1, CYB5R3, EPB41, EPB42, G6PD, GCLC, GPI, GSR, GSS, HK1, NT5C3A, PFKM, PGK1, PIEZO1, PKLR, SEC23B, SLC4A1, SLCO1B1, SLCO1B3, SPTA1, SPTB, TPI1, UGT1A1, UGT1A6, UGT1A7
|Component Test Code*||Component Chart Name||LOINC|
|2012053||Her. Hemolytic Anemia Seq. Specimen||31208-2|
|2012054||Her. Hemolytic Anemia Sequencing Interp||35474-6|
- Dehydrated hereditary stomatocytosis
- Gilbert syndrome
- Glucose-6-phosphate dehydrogenase deficiency
- Hereditary elliptocytosis
- Hereditary pyropoikilocytosis
- Hereditary spherocytosis
- Pyruvate kinase deficiency
- RBC enzymopathies
- RBC membrane defects