Connect Sign In
Lysozyme, Serum
Ordering Recommendation
Aids in diagnosis of acute myelocytic leukemia or other leukemias, sarcoidosis, and infections such as tuberculosis.
New York DOH Approval Status
Specimen Required
Serum separator tube (SST).
Separate serum from cells ASAP or within 2 hours of collection. Transfer 1 mL serum to an ARUP Standard Transport Tube. (Min: 0.4 mL)
Refrigerated.
Hemolyzed, lipemic, icteric, or contaminated specimens.
After separation from cells: Ambient: Unacceptable; Refrigerated: 5 days; Frozen: 1 month.
Methodology
Quantitative Enzyme-Linked Immunosorbent Assay (ELISA)
Performed
Sun, Tue, Thu
Reported
1-5 days
Reference Interval
| Test Number |
Components |
Reference Interval |
|---|---|---|
| Lysozyme, Serum | Less than or equal to 4.50 ug/mL |
Interpretive Data
This test was developed and its performance characteristics determined by ARUP Laboratories. It has not been cleared or approved by the US Food and Drug Administration. This test was performed in a CLIA certified laboratory and is intended for clinical purposes.
| Component |
Interpretation |
|---|---|
| Lysozyme, Serum | 2.75 ug/mL or less ......... Negative 2.76 - 4.50 ug/mL .......... Equivocal 4.51 ug/mL or greater ...... Positive |
Laboratory Developed Test (LDT)
Note
Serum lysozyme levels may be elevated in acute myelomonocytic leukemia (FAB-M4), chronic myelomonocytic leukemia (CMML), and chronic myelocytic leukemia (CML). Increased serum lysozyme activity is present in tuberculosis, sarcoidosis, megaloblastic anemias, acute bacterial infections, ulcerative colitis, regional enteritis, and Crohn disease. Elevated serum lysozyme occurs during severe renal insufficiency, renal transplant rejection, urinary tract infections, pyelonephritis, glomerulonephritis, and nephrosis.
Hotline History
Hotline History
CPT Codes
85549
Components
| Component Test Code* | Component Chart Name | LOINC |
|---|---|---|
| 2012040 | Lysozyme, Serum | 2589-0 |
Aliases
- Muramidase serum
- Serum lysozyme
