Ordering Recommendation

Aids in the differential diagnosis of membranous glomerulonephritis (MGN) or nephrotic syndrome of unknown etiology.

Mnemonic
PLA2R
Methodology

Semi-Quantitative Indirect Fluorescent Antibody

Performed

Mon, Wed, Fri

Reported

1-6 days

New York DOH Approval Status
This test is New York DOH approved.
Specimen Required
Patient Preparation
Collect

Serum Separator Tube

Specimen Preparation

Separate serum from cells ASAP or within 2 hours of collection. Transfer 1 mL serum to an ARUP Standard Transport Tube. (Min: 0.2 mL)

Storage/Transport Temperature

Refrigerated

Unacceptable Conditions

Hemolyzed, hyperlipemic,icteric, heat-treated or contaminated

Remarks
Stability

Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1year

Reference Interval

Less than 1:10

Interpretive Data

A positive result (1:10 or greater) for phospholipase A2 receptor antibody, IgG, in conjunction with other laboratory and clinical findings, supports a diagnosis of primary membranous glomerulonephritis (pMGN).

No compliance statements are in use for this test.

Note

If Phospholipase A2 Receptor Antibody, IgG is positive, then a Phospholipase Receptor A2 Antibody, IgG titer is reported. Additional charges apply.

Hotline History
N/A
CPT Codes

86255; if reflexed, add 86256

Components
Component Test Code* Component Chart Name LOINC
2011829 Phospholipase A2 Receptor, IgG 82991-1
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
Phospholipase A2 Receptor (PLA2R) Antibody, IgG with Reflex to Titer