Ordering Recommendation

Aids in the differential diagnosis of membranous glomerulonephritis (MGN) or nephrotic syndrome of unknown etiology.

New York DOH Approval Status

This test is New York state approved.

Specimen Required

Patient Preparation
Collect

Serum Separator Tube

Specimen Preparation

Separate serum from cells ASAP or within 2 hours of collection. Transfer 1 mL serum to an ARUP Standard Transport Tube. (Min: 0.2 mL)

Storage/Transport Temperature

Refrigerated

Unacceptable Conditions

Hemolyzed, hyperlipemic,icteric, heat-treated or contaminated

Remarks
Stability

Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1year

Methodology

Semi-Quantitative Indirect Fluorescent Antibody

Performed

Mon, Wed, Fri

Reported

1-6 days

Reference Interval

Less than 1:10

Interpretive Data

A positive result (1:10 or greater) for phospholipase A2 receptor antibody, IgG in conjunction with other laboratory and clinical findings, supports a diagnosis of primary membranous glomerulonephritis (pMGN).

Compliance Category

FDA

Note

If Phospholipase A2 Receptor Antibody, IgG is positive, then a Phospholipase Receptor A2 Antibody, IgG titer will be added. Additional charges apply.

Hotline History

N/A

CPT Codes

86255; if reflexed, add 86256

Components

Component Test Code* Component Chart Name LOINC
2011829 Phospholipase A2 Receptor, IgG 82991-1
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.

Aliases

  • Anti-PLA2R
Phospholipase A2 Receptor (PLA2R) Antibody, IgG with Reflex to Titer