Ordering Recommendation

May aid in the diagnosis of chikungunya viral infection during acute phase of disease (>5 days after symptom onset). Testing should also be considered for other arthropod-borne viruses with similar symptomology based on clinical presentation and travel history.

Mnemonic

CHIKPAN

Methodology

Semi-Quantitative Enzyme-Linked Immunosorbent Assay

Performed

Wed

Reported

1-8 days

New York DOH Approval Status

This test is New York DOH approved.

Specimen Required

Patient Preparation
Collect

Serum separator tube.

Specimen Preparation

Separate serum from cells ASAP or within 2 hours of collection. Transfer 1 mL serum to an ARUP Standard Transport Tube. (Min: 0.15 mL) Parallel testing is preferred and convalescent specimens must be received within 30 days from receipt of the acute specimens. Mark specimens plainly as "acute or convalescent."

Storage/Transport Temperature

Refrigerated

Unacceptable Conditions

Contaminated, heat-inactivated, hemolyzed, or severely lipemic specimens.

Remarks
Stability

After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles)

Reference Interval

Test Code Component Reference Interval
2011808 Chikungunya Antibody, IgG 0.79 Index or less Negative: No significant level of Chikungunya IgG antibody detected.
0.80-1.09 Index Equivocal: Questionable presence of Chikungunya IgG antibody detected. Repeat testing in 10-14 days may be helpful.
1.10 Index or greater Positive: Chikungunya IgG antibody detected; suggests current or past infection.
2011810 Chikungunya Antibody, IgM 0.79 Index or less Negative: No significant level of Chikungunya IgM antibody detected.
0.80-1.09 Index Equivocal: Questionable presence of Chikungunya IgM antibody detected. Repeat testing in 10-14 days may be helpful.
1.10 Index or greater Positive: Chikungunya IgM antibody detected.

Interpretive Data

This test was developed and its performance characteristics determined by ARUP Laboratories. It has not been cleared or approved by the US Food and Drug Administration. This test was performed in a CLIA certified laboratory and is intended for clinical purposes.

Compliance Category

Laboratory Developed Test (LDT)

Note

Hotline History

N/A

CPT Codes

86790 x2

Components

Component Test Code* Component Chart Name LOINC
2011809 Chikungunya Antibody, IgG 83068-7
2011811 Chikungunya Antibody, IgM 83067-9
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.

Aliases

Chikungunya Antibodies, IgG and IgM