May aid in the diagnosis of chikungunya viral infection during acute phase of disease (>5 days after symptom onset). Testing should also be considered for other arthropod-borne viruses with similar symptomology based on clinical presentation and travel history.
Semi-Quantitative Enzyme-Linked Immunosorbent Assay
Serum separator tube.
Separate serum from cells ASAP or within 2 hours of collection. Transfer 1 mL serum to an ARUP Standard Transport Tube. (Min: 0.15 mL) Parallel testing is preferred and convalescent specimens must be received within 30 days from receipt of the acute specimens. Mark specimens plainly as "acute or convalescent."
Contaminated, heat-inactivated, hemolyzed, or severely lipemic specimens.
After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles)
|Test Code||Component||Reference Interval|
|2011808||Chikungunya Antibody, IgG||0.79 Index or less||Negative: No significant level of Chikungunya IgG antibody detected.|
|0.80-1.09 Index||Equivocal: Questionable presence of Chikungunya IgG antibody detected. Repeat testing in 10-14 days may be helpful.|
|1.10 Index or greater||Positive: Chikungunya IgG antibody detected; suggests current or past infection.|
|2011810||Chikungunya Antibody, IgM||0.79 Index or less||Negative: No significant level of Chikungunya IgM antibody detected.|
|0.80-1.09 Index||Equivocal: Questionable presence of Chikungunya IgM antibody detected. Repeat testing in 10-14 days may be helpful.|
|1.10 Index or greater||Positive: Chikungunya IgM antibody detected.|
This test was developed and its performance characteristics determined by ARUP Laboratories. It has not been cleared or approved by the US Food and Drug Administration. This test was performed in a CLIA certified laboratory and is intended for clinical purposes.
Laboratory Developed Test (LDT)
|Component Test Code*||Component Chart Name||LOINC|
|2011809||Chikungunya Antibody, IgG||83068-7|
|2011811||Chikungunya Antibody, IgM||83067-9|