Ordering Recommendation

May be used to diagnose chikungunya viral infection during acute phase of disease (>5 days after symptom onset). Testing should also be considered for other arthropod-borne viruses with similar symptomology based on clinical presentation and travel history.

Mnemonic
CHIKM
Methodology

Semi-Quantitative Enzyme-Linked Immunosorbent Assay

Performed

Wed

Reported

1-8 days

New York DOH Approval Status
This test is New York DOH approved.
Specimen Required
Patient Preparation
Collect

Serum separator tube.

Specimen Preparation

Separate serum from cells ASAP or within 2 hours of collection. Transfer 1 mL serum to an ARUP Standard Transport Tube. (Min: 0.15 mL) Parallel testing is preferred and convalescent specimens must be received within 30 days from receipt of the acute specimens. Mark specimens plainly as "acute or convalescent."

Storage/Transport Temperature

Refrigerated.

Unacceptable Conditions

Contaminated, heat-inactivated, hemolyzed, or severely lipemic specimens.

Remarks
Stability

After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles)

Reference Interval
0.79 Index or less Negative: No significant level of Chikungunya IgM antibody detected.
0.80-1.09 Index Equivocal: Questionable presence of Chikungunya IgM antibody detected. Repeat testing in 10-14 days may be helpful.
1.10 Index or greater Positive: Chikungunya IgM antibody detected.

Interpretive Data



Compliance Statement D: For laboratory tests using a manufactured RUO kit. This test was developed and its performance characteristics determined by ARUP Laboratories. The U. S. Food and Drug Administration has not approved or cleared this test; however, FDA clearance or approval is not currently required for clinical use. The results are not intended to be used as the sole means for clinical diagnosis or patient management decisions.

Note
Hotline History
N/A
CPT Codes

86790

Components
Component Test Code* Component Chart Name LOINC
2011811 Chikungunya Antibody, IgM 83067-9
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
Chikungunya Antibody, IgM